#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

The Endocrinology of aging –  short overview


Authors: F. Gabalec;  J. Čáp
Authors‘ workplace: IV. interní hematologická klinika LF UK a FN Hradec Králové
Published in: Kardiol Rev Int Med 2015, 17(2): 181-183
Category: Internal Medicine

Overview

Human life extension in developed countries and related social, medical and economic consequences have become a growing matter of public concern. Impaired physical and mental performance in elderly individuals is not necessarily caused by age and deserves adequate dia­gnosis and therapy. Endocrine causes can be missed due to comorbidities and less frequent typical symp­toms. This review focuses on endocrine changes in aging.

Keywords:
endocrinology –  hormones – aging


Sources

1. United Nations. Department of Economic and Social Affairs. Population Division. World Population Ageing 2013. [online] Available from: http:/ / www.un.org/ en/ development/ desa/ population/ publications/ ageing/ WorldPopulationAgeing2013.shtml.

2. Ústav zdravotnických informací a statistiky ČR. Zdravotnická ročenka České republiky 2013. [online] Dostupné z: http:/ / www.uzis.cz/ publikace/ zdravotnicka‑ rocenka‑ ceske‑ republiky‑ 2013.

3. Starka L. Endokrinologie stárnutí. Intern Med Pro Prax 2002; 6: 280– 289.

4. Boelaert K. Thyroid dysfunction in the elderly. Nat Rev Endocrinol 2013; 9: 194– 204. doi: 10.1038/ nrendo.2013.30.

5. Mazzaferri EL. Management of a solitary thyroid nodule. N Engl J Med 1993; 328: 553– 559. doi: 10.1056/ NEJM199302253280807.

6. Lášticová M. Diabetes mellitus 2. typu ve stáří. Geriatrie a gerontologie 2014; 3: 88– 91.

7. Pelikánová T, Bartoš V. Praktická diabetologie. Praha: Maxdorf 2010.

8. Perrini S, Laviola L, Natalicchio A et al. Associated hormonal declines in aging: DHEAS. J Endocrinol Invest 2005; 28 (Suppl 3): 85– 93.

9. Starka L. Stárnutí u mužů a steroidní hormony 2. díl –  adrenopauza. Interní medicína pro praxi 2012; 14: 257– 260.

10. Arlt W. Dehydroepiandrosterone and ageing. Best Pract Res Clin Endocrinol Metab 2004; 18: 363– 380. doi: 10.1016/ j.beem.2004.02.006.

11. Veldhuis JD, Sharma A, Roelfsema F. Age‑ dependent and gender‑ dependent regulation of hypothalamic‑adrenocorticotropic‑adrenal axis. Endocrinol Metab Clin North Am 2013; 42: 201– 225. doi: 10.1016/ j.ecl.2013.02.002.

12. Zadik Z, Chalew SA, McCarter RJ Jr et al. The influence of age on the 24- hour integrated concentration of growth hormone in normal individuals. J Clin Endocrinol Metab 1985; 60: 513– 516. doi: 10.1210/ jcem‑ 60‑ 3‑ 513.

13. Liu H, Bravata DM, Olkin I et al. Systematic review: the safety and efficacy of growth hormone in the healthy elderly. Ann Intern Med 2007; 146: 104– 115.

14. Junnila RK, List EO, Berryman DE et al. The GH/ IGF‑1 axis in ageing and longevity. Nat Rev Endocrinol 2013; 9: 366– 376. doi: 10.1038/ nrendo.2013.67.

15. Jones CM, Boelaert K. The endocrinology of ageing: A mini‑review. Gerontology 2014. doi: 10.1159/ 000367692.

16. Wu FC, Tajar A, Beynon JM et al. Identification of late‑ onset hypogonadism in middle‑ aged and elderly men. N Engl J Med 2010; 363: 123– 135. doi: 10.1056/ NEJMoa0911101.

17. Bhasin S, Cunningham GR, Hayes FJ et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010; 95: 2536– 2559. doi: 10.1210/ jc.2009‑ 2354.

Labels
Paediatric cardiology Internal medicine Cardiac surgery Cardiology
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#