Do we have sufficient evidence for cardiac resynchronization therapy indication in patients with cardiac failure and NYHA functional classification I-II?

Authors: M. Táborský;  P. Heinc;  M. Fedorco
Authors‘ workplace: I. interní klinika, FN a LF Univerzity Palackého ;  Olomouc
Published in: Kardiol Rev Int Med 2010, 12(2): 80-83


Large scale clinical trials have demonstrated the effects of cardiac resynchronization therapy in patients with New York Heart Association (NYHA) class III/IV, systolic left ventricular function and QRS duration > 120 ms. Two recently published studies have demonstrated that the effects of cardiac resynchronization therapy might also be beneficial in patients with mild heart failure and NYHA class II. More clinical studies are needed to verify the long-term effects of cardiac resynchronization therapy on mortality reduction in this patient cohort.

cardiac resynchronization therapy – heart failure – mortality – reverse remodeling


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