Successful use of sugammadex in morbidly obese patient with a history of postoperative respiratory failure – Case report

Authors: Brabcová Milena;  Vymazal Tomáš
Authors‘ workplace: KARIM, 2. LF UK, Fakultní nemocnice v Motole
Published in: Anest. intenziv. Med., 24, 2013, č. 3, s. 157-159
Category: Anaesthesiology - Case Report


Non-depolarizing muscle relaxing agents are routinely used in nearly two thirds of general anaesthetics. Residual neuromuscular blockade as a major side effect leads to hypoventilation and can contribute to the development of postoperative aspiration and pneumonia. This case report compares the peri-operative course of a patient who underwent the same surgical procedure within tree years. It corroborated the effectiveness and reliability of sugammadex.

residual neuromuscular blockade – hypoventilation – sugammadex


1. Černý, V., Adamus, M., Cvachovec, K., Ševčík, P., Herold, I. Anestezie v České republice 2010 – jednodenní prospektivní observační dotazníková studie. Anest. intenziv. Med., 2011, 22, 1, p. 5–12.

2. Naguib, M. Neuromuscular monitoring and postoperative residual curarisation: a meta-analysis. Br. J. Anaesth., 2007, 98, p. 302–316.

3. Adamus, M., Koutna, J., Neoral, C. The incidence of postoperative residual curarization in the recovery room after rocuronium administration. Rozhl. Chir., 2007, 86, 1, p. 11–16.

4. Cerny, V., Herold, I., Cvachovec, K., Sevcik, P., Adamus, M. Guidelines for managing neuromuscular block: not only Czech beer deserves a taste. Anesth. Analg., 2011, 112, 2, p. 482.

5. Argiriadou, H., Anastasiadis, K., Thomaidou, E., Vasilakos, D. Reversal of neuromuscular blockade with sugammadex in an obese myasthenic patient undergoing thymectomy. J. Anesth., 2011, 25, 2, p. 316–317.

6. Adamus, M., Herold, I. Sugammadex z pohledu medicíny založené na důkazech. Anest. intenziv. Med., 2012, 23, 5, p. 237–240.

7. Murphy, G. S. Residual neuromuscular blockade: incidence, assessment, and relevance in postoperative period. Minerva Anestesiol., 2006, 72, p. 97–109.

8. Berg, H., Roed, J. Residual neuromuscular blockis a risk factor for postoperative pulmonary complications. A prospective, randomised, and blinded study of postoperative pulmonary complications after atracurium, vecuronium and pancuronium. Acta Anaesthesiol. Scand., 1997, 41, p. 1095–1103.

Anaesthesiology, Resuscitation and Inten Intensive Care Medicine

Article was published in

Anaesthesiology and Intensive Care Medicine

Issue 3

2013 Issue 3

Most read in this issue

This topic is also in:

Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.


Don‘t have an account?  Create new account