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Blood transfusion in children and neonates


Authors: Černá Olga
Authors‘ workplace: Klinika dětského a dorostového lékařství Všeobecné fakultní nemocnice a 1. lékařské fakulty Univerzity Karlovy
Published in: Anest. intenziv. Med., 23, 2012, č. 3, s. 152-155
Category: Update in Intensive Care Medicine

Overview

Transfusion of a blood product is an integral part of the comprehensive therapy used in critically ill children and neonates. This population is in general at a high risk of side-effects due to the administered blood transfusion. It is considered that the techniques of preparation of blood products have evolved with the technological advances to increase the safety of the therapy in young children and neonates especially. Unambiguous guidelines are not published yet whereas protocols and indications for blood transfusion and the transfusion practice follow recommendations of specialist societies. They depend on the age of the child, haemoglobin or haematocrit values, clinical condition and diagnosis of the child. A review of evidence-based guidelines and transfusion practices is presented in this article.

Keywords:
transfusion – red blood cell transfusion – thrombocytes transfusion – fresh-frozen plasma


Sources

1. Sharma, S., Sharma, P., Tyler, L. N. Transfusion of blood and blood products: indications and complications. Am. Fam. Physician., 2011, 83, 6, p. 719–724.

2. Bateman, S. T., Lacroix, J., Boven, K. Anemia, blood loss, and blood transfusions in North American children in the intensive care unit. Am. J. respir. Crit. Care Med., 2008, 178, 1, p. 26–33.

3. Lacroix, J., Hébert Transfusion Strategies for Patients in Pediatric Intensive Care Units. N. Engl. J. Med., 2007, 356, p. 1609–1619.

4. Karam, O., Tucci, M., Bateman, S. T., Ducruet, T., Spinella, P. C. Randolph, A. G., Lacroix, J. Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study. Crit. Care, 2010, 14, 2.

5. Kasat, K., Hendricks-Muñoz, K.D., Mally, P. V. Neonatal red blood cell transfusions: searching for better guidelines. Blood Transfus., 201, 1, p. 86–94. doi: 10.2450/2010.0031-10.

6. Singh, R., Visintainer, P. F., Frantz, I. D., Shah, B. L., Meyer, K. M., Favila, S. A., Thomas, M. S., Kent, D. M. Association of necrotizing enterocolitis with anemia and packed red blood cell transfusions in preterm infants. J. Perinatol., 2011, 3, p. 176–182. Epub 2011 Jan 27.

7. Blumberg, N., Heal, J. Platelet transfusion: trigger, dose, benefits and risks Medicine Reports, 2010.

8. Strauss, R. G. Platelet transfusions in neonates: questions and answers. Hematology, 2010, Vol. 3, No. 1.

9. Kenton, A. B., Hegemier, S., Smith, E. O., O’Donovan, D. J., Brandt, M. L., Cass, D. L., Helmrath, M. A., Washburn, K., Weihe, E. K., Fernandes, C. J. Platelet transfusions in infants with necrotizing enterocolitis do not lower mortality but may increase morbidity. J Perinatol., 2005, 25, 3, p. 173–177.

10. Von Lindern et al. Thrombocytopenia in neonates and the risk of intraventricular hemorrhage: a retrospective cohort study BMC. Pediatrics, 2011, 11, p. 16.

11. Triulzi, D. J. Transfusion-related acute lung injury: current concepts for the clinician. Anesth. Analg., 2009, 108, 3, p. 770–776.

12. Sachs, U. J., Wasel, W., Bayat, B., Bohle, R. M., Hattar, K., Berghöfer, H., Reil, A., Bux, J., Bein, G., Santoso, S., Weissmann, N. Mechanism of transfusion-related acute lung injury induced by HLA class II antibodies. Blood, 2011, 13, 117, 2, p. 669–677. Epub 2010 Oct 28.

13. Church, G. D., Price, C., Sanchez, R., Looney, M. R. Transfusion-related acute lung injury in the paediatric patient: Two case reports and a review of the literature. Transfus. Med., 2006, 16, 5, p. 343–348.

Labels
Anaesthesiology, Resuscitation and Inten Intensive Care Medicine
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