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Quality of epidural analgesia and incidence of early complications after major surgery


Authors: Leštianský Boris 1;  Jelínek Milan 1;  Klimeš Jiří 1;  Zvoníčková Dagmar 1;  Pavlík Tomáš 2;  Šrámek Vladimír 1;  Hakl Marek 1
Authors‘ workplace: Anesteziologicko-resuscitační klinika LF MU a FN u sv. Anny v Brně 1;  Institut biostatistiky a analýz Masarykovy univerzity 2
Published in: Anest. intenziv. Med., 23, 2012, č. 1, s. 33-41
Category: Anaesthesiology - Original Paper

Overview

Objective:
The goal of the study was to determine the relationship between chronic vertebral history, difficult epidural insertion, quality of postoperative epidural analgesia and incidence of early complications after major surgery on the first postoperative day.

Design:
Anonymous, questionnaire, non-interventional, observational study.

Setting:
ICUs of the 1st Dept. of General Surgery, Vascular Surgery and Orthopaedics; the Acute Pain Service and the Dept. of Anaesthesiology and Intensive Care Medicine, Masaryk University and University Hospital of St. Anna, Brno, Czech Republic.

Materials and methods:
The total 62 patients came mainly from two groups: thoracotomy (n = 21), insertion height T5–T6 (76.2%), and laparotomy (n = 24), insertion height T10–T11 (62.5%). The secondary group was the arthroplasty group (n = 17), insertion height L4–L5 (100%). The study protocol included peri-operative data (vertebral history, type of procedure, complications during puncture and catheterization of the epidural space) and postoperative evaluation (the quality of pain relief and incidence of early complications). The main groups underwent combined anaesthesia (general anaesthesia: O2 + air + sevoflurane, epidural: 15–20 mg bupivacaine pre-operatively, then10 mg per hour continuously).

Results:
The quality of analgesia (using VAS: 0–3 sufficient, 4–5 uncomfortable, over 5 ~ inadequate analgesia) in the thoracotomy group was sufficient in 57.1%, discomfort in 23.8% and poor in 19.1%. In this group were observed these early complications: sensory deficit in 14.3%, motor deficit in 14.3% and hypotension in 9.6%. In the laparotomy group we observed a higher incidence of difficulties to puncture the epidural space (p = 0.027) in connection with vertebral pathology (p = 0.051). Sufficient analgesia in the laparotomy group was achieved in 75% cases, discomfort occurred in 25% and no patient had poor pain relief (0%). Early complications included sensory deficit in 29.2%, contralateral motor blockade in 4.2% and hypotension in 4.2%. A relationship between a history of chronic vertebral complaints and early complications was not demonstrated in the arthroplasty group (p = 0.637).

Conclusion:
We found good quality of epidural analgesia. The incidence of early complications was also satisfactory. Although the incidence of vertebral pathology in the laparotomy group was relatively high, its impact on the quality of postoperative analgesia was not demonstrated. No severe neurological complications were observed.

Keywords:
vertebral pathology – epidural puncture difficulties – early complications – quality of epidural analgesia


Sources

1. Comerford, D. Troubleshooting. In Middleton, C. Epidural analgesia in acute pain management. Whurr Publisher, 2006, p. 133–159.

2. Hadzic, A. et al. Textbook of regional anaesthesia and acute pain management. 2007, The McGraw-Hill Co., p. 230–267.

3. Van Aken, H. Thoracic epidural anaesthesia and analgesia and outcome. SAJAA, 2008, 14, p. 19–20.

4. Procházka, J. Epidurálně podaný midazolam zesílí účinek lokálního anestetika s opioidem po operacích hrudníku. Bolest, 2010, 13 (1), p. 31–35.

5. Jolly, A. S., Jain, P., Sood, J. Ketamine – current uses and future perspectives. J. Anesth. Clin. Pharmacology, 2007, 23 2, p. 169-181.

6. Shobary, H. M., Sonbul, Z. M., Schricker, T. P. Epidural ketamine for postoperative analgesiain the elderly. M. E. J. Anesth., 2008, 19, p. 1369–1378.

7. Ng, M., J., Goh, H., M. Problems related to epidural analgesia for postoperative pain control. Ann. Acad. Med., 2002, 31, p. 509–515.

8. Lavand, P., De Kock, M. The use of intraoperative epidural or spinal analgesia modulates postoperative hyperlagesia and reduces residual pain after major abdominal surgery. Acta Anaesth. Belg., 2006, 57, p. 373–379.

9. Senard, M. et al. Effect of celecoxib combined with thoracic epidural analgesia on pain after thoracotomy. BJA, 2010, 105, p. 196–200.

10. Taleska, G. et al. Preemptive epidural analgesia with bupivacaine and sufentanyl and the effects of epiduraly added epinephrine for thoracic surgery. Macedonian J. Med. Sciences, 2010, 3, p. 46-53.

11. Wheatley, R. G., Schug, S. A., Watson, D. Safety and efficacy of postoperative epidural analgesia. BJA, 2001, 87, p. 47–61.

12. Hrazdilová, O. et al. Genetika a vnímání akutní bolesti. In XIV. národní kongres ČSARIM. Galén, 2007, s. 82–92.

13. Chris, Steer et al. Best Practice in the Management of Epidural Analgesia in the Hospital Setting. 2010, dostupné na: http://www.britishpainsociety.org/pub_prof_EpiduralAnalgesia2010.pdf

14. Grape, S., Tramer, M. R. Do we need preemptive analgesia for the treatment of postoperative pain? Best pract. Research Clin. Anaesth., 2007, 21, p. 51–63.

15. Berti, M. et al. Patient supplemented epidural analgesia after major abdominal surgery with bupivacaine/fentanyl or ropivacaine/fentanyl. Can. J. Anaesth., 2000, 40, p. 27–32.

16. Michelet, P. et al. Effect of thoracic epidural analgesia on gastric blood flow after oesophagectomy. Acta Anaest. Scand., 2007, 51, 5, p. 587–594.

17. Mourisse, J., Hasenbos, M. A., Gielen, M. J. et al. Epidural bupivacaine, sufentanil or the combination for the postthoracotomy pain. Acta Anaesth. Scand., 1992, 76, p. 70–74.

18. Curatolo, M. Schnider, T. W., Petersen-Felix, S. et al. A direct search procedure to optimize combinations of epidural bupivacaine, fentanyl and clonidine for postoperative analgesia. Anesthesiology, 2000, 92, p. 325–327.

19. Ginosar, Y., Raley, E. T., Angst, M. S. The site of action of epidural fentanyl in humans: the difference between bolus and infusion administration. Anesth. Analg., 2003, 97, p. 1428–1438.

20. Fleckenstein, J., Kramer, S., Offenbacher, M. et al. Etoricoxib – preemptive and postoperative analgesia (EPPA) in patients with laparotomy and thoracotomy – design and protocols. Trials 2010, 11:66, doi:10.1186/1745-6215-11-66.

Labels
Anaesthesiology, Resuscitation and Inten Intensive Care Medicine
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