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Self-Administration of Romiplostim in Chronic Immune Thrombocytopenia: Analysis of 3 Studies

23. 2. 2021 Source: Immune Thrombocytopenia

A post hoc analysis of 3 clinical studies showed that in adult patients with chronic immune thrombocytopenia (ITP), self-administration of romiplostim achieves comparable efficacy and safety as when the drug is administered by a healthcare professional.

kardiolog

Noonan Syndrome (Not Just) in the Pediatric Cardiologist's Office

Noonan Syndrome (NS) is a genetically determined disease associated with a high prevalence of (not just) congenital heart defects. When is it necessary to consider it in a cardiologist's office,…
23. 2. 2021 Source: Growth Disorders
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INFOGRAPHIC: Migraine Treatment Without Mistakes

A practical guide on how to proceed with the diagnosis of migraine, so that the treatment is effective and tailored to the patient.
22. 2. 2021 Source: Migraine
srdce_infografika_selhani_kardiologie

Efficacy of Dabigatran on Left Atrial Appendage Thrombus in Patients with Atrial Fibrillation

The direct thrombin inhibitor dabigatran has shown interesting efficacy in a smaller clinical study in patients with atrial fibrillation and a thrombus in the left atrial appendage. Chinese authors…
22. 2. 2021 Source: Anticoagulant Treatment
leky lék pod lupou srovnání léků farmaka účinná látka

Micronized Diosmin and Flavonoid Fraction –⁠ What Do They Have in Common?

Micronized diosmin and micronized purified flavonoid fraction are medications from the flavonoid group that are used as venopharmaceuticals/venoprotectives in the treatment of chronic venous…
22. 2. 2021 Source: Venous Insufficiency
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Do antiglaucoma drugs induce inflammation and irritation on the eye surface? Results of a 2-year randomized study

Eye drops for glaucoma treatment may contain preservatives responsible for eye irritation and possibly chronic inflammation. The study presented below is the first to compare the profile of…
18. 2. 2021 Source: Treatment of Glaucoma
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Antiglaucoma Eye Drops with Preservatives –⁠ Higher Likelihood of Glaucoma Surgery?

A recently published French study sought to answer the question of whether there is a connection between the presence of preservatives in antiglaucoma eye drops and the probability of undergoing…
18. 2. 2021 Source: Treatment of Glaucoma
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Quantitative CT as a New Tool for Evaluating COPD in Alpha-1 Antitrypsin Deficiency

For such a rare hereditary disorder as alpha-1 antitrypsin deficiency (AATD), we have so far used functional tests as the main tool for monitoring the progression of lung disease. Now we are moving…
18. 2. 2021 Source: Deficiency of Alpha-1-Antitrypsin
léky_lékař

Intravenous Thrombolysis in Ischemic Stroke Patients on Dabigatran Treatment

What are the outcomes of performing intravenous thrombolysis in patients with acute ischemic stroke after reversing the anticoagulant effect of dabigatran with idarucizumab? The answer is provided by…
18. 2. 2021 Source: Anticoagulant Treatment
Lactobacillus reuteri

Lactobacillus reuteri −⁠ a natural probiotic with lifelong significance

Probiotics are often given to newborns within the first few days of life to alleviate infantile colic. However, the role of probiotic treatment in protecting infants from infections, even into their…
16. 2. 2021 Source: GI, colic and microbiome
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State of the Intestinal Microbiome and COVID-19 Infection −⁠ Possible Correlations

Some patients infected with the SARS-CoV-2 virus exhibit gastrointestinal symptoms, including diarrhea, during the course of COVID-19. Current knowledge suggests that COVID-19 symptoms are related,…
16. 2. 2021 Source: GI, colic and microbiome
Transfuze_krevni_banka

Safety Profile of Antiemetic Therapy in Patients Preparing for Hematopoietic Stem Cell Transplantation

An observational study conducted at a university clinic in Barcelona investigated the safety of the fixed combination of palonosetron and netupitant in patients preparing for hematopoietic stem cell…
15. 2. 2021 Source: Antiemetic Therapy
Zvracení_nevolnot_žena_toaleta

Intravenous Fixed Combination NEPA in the Prevention of Chemotherapy-Induced Vomiting

Summary data from several studies were used by the authors of the following analysis to evaluate the efficacy of the intravenous and oral forms of the fixed combination NEPA (netupitant/fosnetupitant…
15. 2. 2021 Source: Antiemetic Therapy
Plíce_snímek_lékař_pacient

Brigatinib vs. Crizotinib in the Treatment of ALK-Positive NSCLC –⁠ Results of the Second Interim Analysis of the ALTA-1L Study

The anaplastic lymphoma kinase inhibitor brigatinib demonstrated superiority over crizotinib in the first interim analysis of the ALTA-1L study in terms of progression-free survival and improvement…
15. 2. 2021 Source: Non-Small Cell Lung Cancer
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Good Efficacy of Brigatinib After Failure of 2nd Generation ALK Inhibitors

Brigatinib is commonly used in the treatment of ALK-positive non-small cell lung cancer (NSCLC) in the 2nd line after progression on a 1st-generation ALK inhibitor, crizotinib. American scientists in…
15. 2. 2021 Source: Non-Small Cell Lung Cancer
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