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prohlídka lékař pacient nemocnice medicína vyšetření pomoc ruce

Does olaparib improve overall survival in patients with recurrent ovarian cancer and BRCA mutation?

13. 2. 2021 Source: Ovarian and Breast Cancer

Olaparib, a poly(ADP-ribose) polymerase (PARP) enzyme inhibitor, in tablet form is indicated, among other things, for the maintenance treatment of adult patients with platinum-sensitive recurrent high-grade epithelial ovarian, fallopian tube, or primary peritoneal cancer who respond (complete or partial response) to platinum-based chemotherapy. Its efficacy in this indication in terms of prolonging progression-free survival and overall survival was addressed by the phase III study presented below.

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Trazodone in the Treatment of Depressive Disorder –⁠ A Case Study

Presented by MUDr. Sylva Racková, Ph.D. Psychiatric Clinic, Plzeň
12. 2. 2021 Source: Depression and Anxiety
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Hydrotherapy in the Treatment of Non-Healing Wounds

For the treatment of wounds, it is crucial how they are managed during the cleaning and granulation phases. For most non-healing wounds, so-called Hydrotherapy (treatment with hydroresponsive…
10. 2. 2021 Source: Wound Healing
ockovani covid-19 muž

International Recommendations for COVID-19 Vaccination in People with Bleeding Disorders

At the end of December 2020, international guidelines for COVID-19 vaccination in people with bleeding disorders were published on the World Federation of Hemophilia (WFH) website. We present a basic…
8. 2. 2021 Source: Hemophilia
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COVID-19: Specifics of Care for Individuals with Congenital Bleeding Disorders

The COVID-19 pandemic has significantly impacted nearly all medical fields. Alongside direct care focused on seriously ill patients, the pandemic also affects the care of chronic patients, including…
8. 2. 2021 Source: Hemophilia
plice dychani nemocnice covid oxygenová maska

Invasive Pulmonary Aspergillosis –⁠ A Common Accompanying Infection in Patients with Severe or Critical Course of COVID-19

Findings based on a literature review conducted and published in September 2020 show the occurrence of invasive pulmonary aspergillosis (IPA) in 19.6–33.3% of patients with a severe or critical…
8. 2. 2021 Source: Anti-Infectives
Starší pacient

Trifluridine/Tipiracil in the 3rd Line Treatment of mCRC −⁠ Case Study

The following case study describes the treatment of a patient with metastatic colorectal cancer (mCRC) and the benefits of trifluridine/tipiracil within the therapeutic algorithm.
3. 2. 2021 Source: Treatment of Gastrointestinal Carcinomas
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Atectura® and Enerzair®: new fixed dual and triple combination in the treatment of bronchial asthma

In mid-2020, the European Commission approved two new fixed combinations of drugs by Novartis for patients with uncontrolled asthma –⁠ the dual combination Atectura® (LABA+ICS) and the triple…
28. 1. 2021 Source: Asthma under control
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Recent Advances in Physiotherapy for Hemophiliacs

Physiotherapy specifically focuses on movement and the movement potential of the individual, with the purpose of restoring or maintaining maximum mobility and functional abilities throughout life.…
28. 1. 2021 Source: Hemophilia with Movement
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Turoctocog Alfa Pegol with Extended Half-Life in the Treatment of Severe Hemophilia A

GlycoPEGylated recombinant factor VIII (rFVIII) with an extended half-life, turoctocog alfa pegol, has demonstrated prophylactic efficacy in patients with severe hemophilia A aged over 12. This…
28. 1. 2021 Source: Hemophilia with Movement
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Candesartan Could Ameliorate the Cytokine Storm in COVID-19 Infection

Scientists from Bethesda, USA, experimentally found the upregulation of the same genes during COVID-19 infection as with the action of glutamate (simulating aging and Alzheimer's disease) and the…
27. 1. 2021 Source: Sartans in the Treatment of Hypertension

Is the efficacy of bisoprolol in secondary prevention of acute myocardial infarction in patients after percutaneous coronary intervention comparable to carvedilol?

Beta-blockers (BB) are recommended for all patients after percutaneous coronary intervention (PCI) as part of secondary prevention of acute myocardial infarction (AMI). The study presented below…
26. 1. 2021 Source: Cardiovascular Continuum
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How to Care for Dialysis Patients in the Times of COVID-19

More than 2 million people worldwide undergo maintenance hemodialysis in outpatient centers. Effective prevention of the spread of infection caused by the SARS-CoV-2 coronavirus within the care…
26. 1. 2021 Source: Chronic Kidney Disease
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How do Hemodialysis Patients Perceive the Coronavirus Pandemic? Survey Results

Hemodialysis patients are at higher risk of SARS-CoV-2 infection due to repeated visits to medical facilities. Additionally, these are often older and comorbid patients living in nursing homes. This…
26. 1. 2021 Source: Chronic Kidney Disease
mlada zena udiv zprava nepochopeni neciti dobre

Increased Sympathetic Activity in Patients with Masked Uncontrolled Hypertension

Not all hypertensive patients who have normal blood pressure readings in the doctor's office actually have controlled hypertension. Recent studies suggest that so-called masked uncontrolled…
25. 1. 2021 Source: Cardiovascular Continuum
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