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Older patients with CLL and comorbidities: an option for treatment with immunotherapy without chemotherapy?

19. 1. 2021 Source: Chronic Lymphocytic Leukemia

Is it time to treat chronic lymphocytic leukemia (CLL) without chemotherapy? The authors of a recently published article in the Expert Review of Hematology journal attempted to answer this question.

Recommend Erdostein for children when treating with amoxicillin –⁠ symptoms of cough improve in almost 50% of cases within 3 days

Acute respiratory infections are usually treated empirically in primary care as the causative agent is not known. Amoxicillin is among the most commonly chosen antibiotics. Erdostein is a suitable…
19. 1. 2021 Source: Cough Therapy
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Fixed Combination of Candesartan/Amlodipine in the Treatment of Arterial Hypertension

Arterial hypertension is a significant cardiovascular risk factor. A variety of antihypertensives are used in therapy, both in monotherapy and combination treatment. Often, it is necessary to treat…
19. 1. 2021 Source: Sartans in the Treatment of Hypertension
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Efficacy and Safety of Preservative-Free Latanoprost in the Treatment of Open-Angle Glaucoma and Elevated Intraocular Pressure –⁠ Results of a Meta-Analysis

Many eye drops for the treatment of glaucoma still contain preservatives today. However, these can cause eye irritation, so non-preservative formulations should be preferred. The following…
14. 1. 2021 Source: Treatment of Glaucoma
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Can We Reach Brain Metastases of Lung Cancer with Anti-EGFR Targeted Therapy?

Information on the penetration of epidermal growth factor receptor tyrosine kinase inhibitors (anti-EGFR TKIs) through the blood-brain barrier primarily comes from preclinical testing. In clinical…
11. 1. 2021 Source: Lung Cancer
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San Antonio: Results of Breast Cancer Treatment with Combination of Pertuzumab, Trastuzumab, and AI After 6 Years

The virtual conference dedicated to breast cancer, which took place December 8–11 in San Antonio, USA (San Antonio Breast Cancer Symposium; SABCS 2020), presented, among other things, the results of…
11. 1. 2021 Source: Breast Carcinoma
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Targeted Treatment of HER2-Positive Breast Tumors –⁠ Updates from ESMO 2020 Congress

The recent European Society for Medical Oncology (ESMO) Congress took place virtually. We bring you a brief summary of the presentations related to the treatment of HER2-positive breast tumors.
11. 1. 2021 Source: Breast Carcinoma
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Diagnosis, Treatment, and Outcomes Achieved in Patients with Non-Small-Cell Lung Cancer in Central Europe

In June 2020, the journal Radiology and Oncology published the results of an analysis of data from patients with stage III non-small-cell lung cancer (NSCLC) from a Central European registry. A large…
6. 1. 2021 Source: Lung Cancer
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New Alternative in the Treatment of Diffuse Large B-cell Lymphoma

For patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who are not suitable candidates for autologous stem cell transplantation, a wide range of treatment regimens is…
4. 1. 2021 Source: Non-Hodgkin Lymphomas and CLL
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ASH 2020: Efficacy and Safety of Emicizumab in Long-term Follow-up

At the virtual meeting of the American Society of Hematology (ASH) in December 2020, the latest data concerning the long-term follow-up of participants in the HAVEN 1−4 clinical trials with…
4. 1. 2021 Source: Quality Life Even with Hemophilia
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ASH 2020: Two Real-World Perspectives on Experiences with Emicizumab Prophylaxis

Data presented at the ASH 2020 congress bring interesting insights regarding the administration of emicizumab in real clinical practice. It provides comprehensive information on the relatively high…
4. 1. 2021 Source: Quality Life Even with Hemophilia
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Frequency of Mutations in Genes Predisposing to Ovarian Cancer in the Czech Population

The authors of a Czech study evaluating the occurrence of mutations in tumor-predisposing genes for ovarian cancer hypothesized that if their occurrence in patients with this diagnosis was…
18. 12. 2020 Source: Ovarian and Breast Cancer
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Factors Influencing the Occurrence of Prosthetic Stomatitis in Patients with Complete Denture

Dental dentures are removable replacements made for partial or complete loss of teeth. Quality denture treatment is a long-lasting process in which oral hygiene and denture hygiene play a key role.
18. 12. 2020 Source: Optimal Care of Dentures
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Ceftarolin Fosamil in Patients with Complicated Skin and Soft Tissue Infections Admitted to ICU

In a recently published data analysis from the COVERS 3 study, the antibiotic ceftarolin fosamil was evaluated in patients with complicated skin and soft tissue infections (cSSTI) admitted to the…
17. 12. 2020 Source: Anti-Infectives
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Long-term results of alpha-1-antitrypsin deficiency treatment –⁠ RAPID program

RAPID/RAPID Extension is the largest clinical program to date that has confirmed the benefit of alpha-1-antitrypsin inhibitor in the treatment of chronic obstructive pulmonary disease (COPD)…
17. 12. 2020 Source: Deficiency of Alpha-1-Antitrypsin
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