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Can antihypertensive treatment also have a beneficial effect on neurocognitive functions?

14. 6. 2021 Source: Sartans in the Treatment of Hypertension

Observational studies suggest that a desirable side effect of AT1 receptor blockers for angiotensin II (sartans) could be cognitive protection of patients. A randomized study published last year evaluated the potential positive impact of candesartan and lisinopril on neurocognitive functions in older patients with mild cognitive impairment (MCI).

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Are there mutual interactions between candesartan and amlodipine in the combination therapy of hypertension?

Monotherapy is often insufficient in the treatment of hypertension; however, combining antihypertensives with different mechanisms of action can be complicated by their mutual interactions.…

14. 6. 2021 Source: Sartans in the Treatment of Hypertension

INFOGRAPHIC: LDL Cholesterol -⁠ Recommended Target Values

Elevated levels of LDL cholesterol are a significant risk factor for cardiovascular diseases, which remain the most common cause of death among adult Czechs. We have strong evidence about who and how...

11. 6. 2021 Source: Chronic Heart Failure and Lipidology

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How did alemtuzumab fare in real clinical practice?

A study published by authors from the University of Massachusetts in January this year in the journal Multiple Sclerosis and Related Disorders focused on the effectiveness and safety of alemtuzumab.…

11. 6. 2021 Source: Multiple Sclerosis

Reduction of LDL Cholesterol in the Prevention of Cardiovascular Morbidity and Mortality –⁠ Results of a Large Meta-Analysis

Elevated LDL cholesterol (LDL-c) is one of the main causes of atherosclerosis. The meta-analysis presented below examined the effect of reducing its levels on the risk of cardiovascular (CV)…

11. 6. 2021 Source: Chronic Heart Failure and Lipidology

Does Peritoneal Dialysis Have Its Place Even in Acute Cases?

In patients who urgently need to replace kidney function, hemodialysis traditionally played the role of the gold standard. Can peritoneal dialysis fully replace it?

8. 6. 2021 Source: Chronic Kidney Disease

Safety of Urgent Initiation of Peritoneal Dialysis

In case of urgent need for kidney function replacement, hemodialysis (HD) with a temporary venous catheter has long been the standard solution. However, it has several disadvantages such as increased…

8. 6. 2021 Source: Chronic Kidney Disease

Importance of Home Parenteral Therapy: ESPEN Recommendations from 2020

Home parenteral therapy currently plays a crucial role in the treatment and prevention of malnutrition in specific patient groups. The European Society for Clinical Nutrition and Metabolism (ESPEN)…

7. 6. 2021 Source: Parenteral Nutrition

Vitamins in Prevention and Treatment of COVID-19

Vitamin supplementation is an important part of therapy for various diseases, and it seems that they also play a significant role in the case of COVID-19. What kind of role? It's certainly not a…

7. 6. 2021 Source: Parenteral Nutrition

Current Results of Brigatinib in the Treatment of Lung Cancer

The results of the primary analysis showed a significant extension of PFS in patients with non-small cell lung cancer (NSCLC) treated with brigatinib compared to crizotinib. The recently published…

4. 6. 2021 Source: Non-Small Cell Lung Cancer

Position of the Aclidinium-Bromide/Formoterol-Fumarate Combination in COPD Treatment According to Current Recommendations

Dual bronchodilator therapy, which combines long-acting muscarinic antagonists (LAMA) and long-acting β-agonists (LABA), has become an integral part of the treatment for chronic obstructive pulmonary…

3. 6. 2021 Source: Treatment of Asthma and COPD

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