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N9-GP in Previously Treated Pediatric Patients with Hemophilia B –⁠ Extended Follow-up

4. 10. 2023 Source: Hemophilia with Movement

An analysis of extended treatment with nonacog alfa pegol (N9-GP) in pediatric patients with hemophilia B evaluated the long-term safety and effectiveness of this prophylactic modality.

artroplastika kyčelního a kolenního kloubu

Pain Management in Patients After Hip and Knee Arthroplasty –⁠ Data from Clinical Practice

Inadequate analgesia after hip and knee arthroplasty can result in delayed postoperative recovery accompanied by chronic pain. The retrospective study presented below compared the efficacy of…

3. 10. 2023 Source: Analgesia

Subcutaneous Immunoglobulin Therapy in Patients with Secondary Immunodeficiency –⁠ Real-World Data

Even in patients with secondary immunodeficiency (SID), immunoglobulin substitution can be indicated. Intravenous (IVIG) therapy is considered effective based on studies, but subcutaneous (SCIG) therapy...

2. 10. 2023 Source: Primary and Secondary Immunodeficiencies

Romiplostim in Newly Diagnosed ITP Resistant to 1st Line Treatment –⁠ Case Study

In patients with immune thrombocytopenia (ITP), effectively stopping and controlling bleeding can be complicated in some cases. This includes scenarios such as open wounds. One way to stabilize…

2. 10. 2023 Source: Immune Thrombocytopenia

Romiplostim in ITP Treatment –⁠ Data from German Clinical Practice

Real-world clinical practice data from Germany confirm the beneficial effect and safety profile of romiplostim in patients with immune thrombocytopenia (ITP), both newly diagnosed, persistent, and…

2. 10. 2023 Source: Immune Thrombocytopenia

Invasive Pneumococcal Disease –⁠ Current Czech Data

The number of reported cases of invasive pneumococcal disease (IPD) returned to levels comparable to those before the COVID-19 pandemic in 2022. Regarding age-specific morbidity, the most at-risk…

2. 10. 2023 Source: Regular Vaccination

Do Gliflozins Affect the Need to Use Diuretics?

Sodium-glucose cotransporter 2 inhibitors (SGLT2i, i.e., gliflozins) have advanced from their initial role in reducing hyperglycemia in the treatment of type 2 diabetes mellitus (DM2) to…

1. 10. 2023 Source: Heart Failure

INTERACTIVE CASE STUDY: Treatment of glaucoma medications without preservatives –⁠ current trend

The use of glaucoma medications without preservatives has been a trend in recent years. You can try their clinical application in the role of a prescribing doctor in an interactive case study.…

28. 9. 2023 Source: Treatment of Glaucoma

Rapid Strengthening and Long-term Stabilization –⁠ New Strategy for Sequential Treatment of Severe Osteoporosis

Osteoanabolics have long been considered a treatment modality for osteoporosis that is only considered when antiresorptive medication lacks the desired efficacy. However, their role has been shifting…

27. 9. 2023 Source: Osteoporosis – Trends in Sequential Therapy

Inhibition of Sclerostin in Osteoporosis Therapy

Romosozumab, a subcutaneously administered antibody against sclerostin, is one of the most potent osteoanabolics and appears to be a highly effective modality in the treatment of postmenopausal…

27. 9. 2023 Source: Osteoporosis – Trends in Sequential Therapy

Doc. Tomáš Gabrhelík: Pain treatment should be seriously addressed by all fields, especially in seniors

Chronic pain is often underestimated, especially in older and polymorbid patients. On the other hand, during self-treatment, many patients use inappropriate medication for a long time. The treatment…

27. 9. 2023 Source: Analgesia

Three times on the topic of therapeutic cannabis usage possibilities –⁠ case studies from Czech practice

The following case studies from real Czech practice describe three cases of patients with various diagnoses, indicated for cannabis extract administration. In the first case, there was significant…

27. 9. 2023 Source: Medical Cannabis

Ocrelizumab in the treatment of multiple sclerosis in real-world practice –⁠ a systematic review of published studies

In controlled study programs, ocrelizumab has demonstrated beneficial effects on improving clinical parameters in patients with multiple sclerosis, such as the annual relapse rate or confirmed…

27. 9. 2023 Source: Neurology - Multiple Sclerosis

Innovation in Wound Healing: Zetuvit Plus Silicone Border for Optimal Wound Exudate Management

Excessive wound exudate can lead to delayed healing, skin damage around the wound, or leakage under the chosen dressing. Zetuvit Plus Silicone Border dressing with high absorbent and retention…

26. 9. 2023 Source: Wound Healing

Current Data of Tofacitinib in the Treatment of IBD: What Improvements in Endoscopic and Histologic Outcomes Can Be Achieved?

The oral Janus kinase inhibitor (JAKi) tofacitinib is currently approved for the treatment of moderately to severely active ulcerative colitis (UC). Its efficacy and safety in this indication have…

20. 9. 2023 Source: Intestinal Inflammations

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