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Identification of patients with advanced Parkinson's disease suitable for device-aided therapy (DAT)

14. 9. 2023 Source: Parkinson's Disease

To properly implement device-aided therapy in Parkinson's disease (PD) management, it is essential to timely identify patients in advanced stages of the disease who might benefit from this therapeutic approach. We summarize the useful tools that doctors can use to find these patients.

Do real-world clinical practice data confirm the results of cenobamate treatment in the clinical program?

A recent study by Spanish authors presents the largest dataset of patients with published cenobamate treatment results under prolonged observation in real-world clinical practice at the time of…

13. 9. 2023 Source: Epilepsy

Cenobamate in the Therapy of Pharmacoresistant Epilepsy in a Warfarinized Patient –⁠ A Case Study

A case study from Czech practice presents a patient with pharmacoresistant epilepsy and concurrent warfarin medication for heart valve replacement, where the INR value remained within the…

13. 9. 2023 Source: Epilepsy

Meta-analysis of Efficacy and Safety of Antidiabetics in Treating Gestational DM

What efficacy and safety do insulin, metformin, or the sulfonylurea derivative glibenclamide (glyburide) offer in lowering glucose levels in women with gestational diabetes? The authors of a…

13. 9. 2023 Source: Modern Treatment of Diabetes

Revolutionary Change in the Paradigm of Multiple Sclerosis (MS) Treatment in the Czech Republic

At the beginning of last year, there was a revolutionary change in the paradigm of multiple sclerosis (MS) treatment in the Czech Republic. Patients with MS and an unfavorable prognosis no longer have...

11. 9. 2023 Source: Neurology - Multiple Sclerosis

How to Determine the Optimal Target Value of Intraocular Pressure in Glaucoma Treatment?

Glaucoma remains the second most common cause of blindness in Europe. Therapy needs to be individualized with regard to the severity of the condition, expected lifespan, and the rate of disease…

8. 9. 2023 Source: Treatment of Glaucoma

Hypertrophic Cardiomyopathy: When Bigger Does Not Mean Better

Hypertrophic cardiomyopathy (HCM) is a hereditary disease that, in some patients, proceeds asymptomatically, while others struggle with arrhythmias or heart failure, and in some individuals, the…

7. 9. 2023 Source: Hypertrophic Cardiomyopathy (HCM)

Why does the heart enlarge? Myosin mutation and hypertrophic cardiomyopathy may be the culprits

The genetic basis of hypertrophic cardiomyopathy was discovered only about a quarter-century ago. Since then, researchers have gathered a wealth of knowledge about the effects of causal mutations.…

7. 9. 2023 Source: Hypertrophic Cardiomyopathy (HCM)

Current View on Gestational Diabetes Mellitus in Theory and Practice

We dedicated one of the episodes of our podcast meditalks+ to the issue of gestational diabetes mellitus (GDM), focusing on aspects of care related to general practitioners. In a conversation with …

7. 9. 2023 Source: Modern Treatment of Diabetes

ESMO Recommendations for the Treatment of Low-Risk Myelodysplastic Syndrome

The priority in the treatment of low-risk myelodysplastic syndrome (MDS) is managing cytopenia, primarily anemia, as well as neutropenia and thrombocytopenia. The following summary of recommendations…

6. 9. 2023 Source: proLékaře.cz

Effect of Luspatercept Treatment in Patients with MDS/MPN-RS-T

The presented post hoc analysis of the MEDALIST study demonstrates the effect and good tolerance of luspatercept in the rare disease from the myelodysplasia group −⁠ MDS/MPN-RS-T.

6. 9. 2023 Source: proLékaře.cz

Association between Hypothyroidism, Depression, and Anxiety Disorder –⁠ Results of Meta-Analyses

The prevalence of autoimmune thyroiditis in the USA ranges between 4 and 13%. Subclinical hypothyroidism affects 3–8.5% of the general population. Patients with this condition are at risk not only…

6. 9. 2023 Source: Thyroid Disorders

A Look at Tongue and Its Care from the Perspective of Western and Traditional Chinese Medicine

The tongue is a valuable diagnostic tool used in both Traditional Chinese Medicine (TCM) and Western medicine. While the approaches to tongue care between these two medical systems differ…

6. 9. 2023 Source: Dental Care

Management of Adverse Effects During Maintenance Treatment of AML Patients

The randomized phase III study QUAZAR AML-001 evaluated the maintenance treatment of acute myeloid leukemia (AML) in patients after first remission. The following text summarizes the findings…

4. 9. 2023 Source: Acute Myeloid Leukemia

SCOPE 2021 –⁠ State of Osteoporosis and Its Treatment in European Countries

The SCOPE 2021 project (The Scorecard for Osteoporosis in Europe) by the International Osteoporosis Foundation (IOF) gathered and tabulated data from 29 European countries on the burden of…

4. 9. 2023 Source: Osteoporosis – Trends in Sequential Therapy

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