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News ITP from the Patients' Perspective: How It Affects Their Lives and Which Needs They Find Unmet?

In recent years, new therapeutic options for immune thrombocytopenia (ITP) have been introduced, which are effective for many patients and have significantly improved their quality of life. However, it remains crucial to listen to patients' experiences with treatment and any unmet needs they may have. A meeting of the Platelet Disorder Support Association brought forth many interesting findings and shared experiences. So what troubles ITP patients the most?

Source: Immune Thrombocytopenia 28. 11. 2022

News Cardio-Renal-Metabolic Syndrome?

The association between type 2 diabetes (DM2) and atherosclerotic cardiovascular disease (ASCVD) is often referred to as cardiometabolic syndrome, while the relationship between chronic kidney disease (CKD) and heart failure (HF) is known as cardiorenal syndrome. Additionally, an increased prevalence of ASCVD, CKD, and HF is known among patients with type 2 diabetes. A recent study investigated the hypothesis that both syndromes constitute a single entity −⁠ the so-called cardio-renal-metabolic syndrome.

Source: Diabetes 18. 10. 2023

News Current Insights into the Etiology of Community Pneumonia: Pneumococci Still Leading?

The etiology of community-acquired pneumonias has undergone certain changes since the beginning of the antibiotic era. According to current guidelines, it is still recommended to initiate empirical antibiotic therapy upon diagnosing community-acquired pneumonia. However, there are certain concerns associated with the recommendation of empirical antibiotic therapy, especially regarding the increasing occurrence of bacterial antibiotic resistance. The aim of the study presented below was to specify the most frequently isolated pathogens of community-acquired pneumonia between 1945 and 2020.

Source: Anti-Infectives 25. 3. 2022

News How to Maintain Hygiene for Incontinent Patients Without Using Water?

Urinary incontinence brings numerous health risks. Due to frequent continuous contact of aggressive urine with the skin, a significant number of patients develop skin complications such as eczema, rashes, or even pressure sores. Maximum care should therefore be devoted to the hygiene of intimate areas in all incontinent patients.

Source: Incontinence 29. 8. 2022

News Patient with Generalized Melanoma Treated with Nivolumab with Long-Term Response after Previous Failure of Combined Chemoimmunotherapy

Source: Case Studies from Immunooncology 11. 9. 2020

News Lactobacillus reuteri −⁠ a natural probiotic with lifelong significance

Probiotics are often given to newborns within the first few days of life to alleviate infantile colic. However, the role of probiotic treatment in protecting infants from infections, even into their adult life, is a growing area of research interest. Which natural probiotic strains have verified immunomodulatory properties and is it suitable to administer them alongside breast milk?

Source: GI, colic and microbiome 16. 2. 2021

Články časopisu Amniotic fluid embolism –⁠ review

Author of the article: A. Černý, A. Pařízek, Patrik Šimják Source: Česká gynekologie | 4/2014 1. 8. 2014

Články časopisu Radiotherapy and radiosensitivity syndromes in DNA repair gene mutations

Author of the article: R. Lohynská, Z. Pechačová, E. Mazaná, J. Čejková, A. Nováková-Jirešová, J. Hornová, M. Langová Source: Klinická onkologie | 2/2022 12. 4. 2022

Články časopisu Examination of circulating tumor cells in renal carcinoma

Author of the article: Petr Klézl, Jindřich Šonský, Eliška Pospíšilová, Katarína Kološtová, Vladimír Bobek, Robert Grill Source: Česká urologie | 2/2020 11. 6. 2020

News ACC 2023 Expert Consensus: How to Optimize Diagnosis and Treatment of Heart Failure with Preserved EF LK

Heart failure (HF) remains a significant cause of morbidity and mortality, with the incidence and prevalence of HF with preserved left ventricular ejection fraction (HFpEF) rising. The following document focuses on individuals with HFpEF and supports the principles of evidence-based diagnosis and treatment of HF from 2022. It emphasizes the need for individualized care and multidisciplinary cooperation.

Source: Heart Failure 14. 3. 2024

Články časopisu Cerebral venous thrombosis during pregnancy

Author of the article: V. Smetanskyi, A. Šefčíková, A. Dörr Source: Česká gynekologie | 2/2018 4. 6. 2018

News Treatment of Immune Thrombocytopenia: Choice of TPO Mimetics in Clinical Practice

Real-world data show that the administration of thrombopoietin receptor agonists in immune thrombocytopenia leads to a high percentage of treatment responses, and in some patients, it is possible to achieve a stable response without the need for further treatment after discontinuation.

Source: Immune Thrombocytopenia 20. 2. 2020

Články časopisu

Author of the article: Martin Pretl, Zuzana Lattová, Andrea Plíhalovájan Polák, Kateřina Westlake Source: Časopis lékařů českých | 5/2019 7. 11. 2019

News Prediabetes through the lens of current data and findings −⁠ and why hurry with intervention

Type 2 diabetes mellitus (DM2) is one of the most common causes of premature morbidity and mortality worldwide. The most serious impact on the health of the organism is mainly due to the macrovascular complications of this disease. However, their occurrence was often recorded before the diagnosis of DM2 was confirmed. Prediabetes itself thus represents a condition associated with the risk of developing cardiovascular (CV) complications with all their prognostic implications for patients.

Source: Diabetes 27. 7. 2022

News Complete remission of ALK-positive lung cancer in a patient after multiple lines of targeted therapy –⁠ a case study

Targeted treatment for driving oncogenic mutations has significantly improved outcomes for patients with ALK-positive non-small cell lung cancer (NSCLC) as well. A case study was recently published in the journal Frontiers in Oncology of a patient with advanced disease who achieved complete remission after several lines of therapy.

Source: Genetic Profile and Treatment of NSCLC 27. 12. 2021