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News Effectiveness of Dietary Intervention in Irritable Bowel Syndrome –⁠ Results of a Network Meta-Analysis

A low FODMAP diet is often recommended to alleviate symptoms of irritable bowel syndrome (IBS). Although several randomized studies have been conducted to assess the effectiveness of this diet, a systematic evaluation has yet to be available, and individual studies have used various control interventions. Therefore, an international team of researchers decided to prepare a systematic literature review with a network analysis, recently published in the journal Gut.

Source: Irritable Bowel Syndrome 12. 10. 2022

News Undiagnosed Hereditary Angioedema in Pregnancy –⁠ Case Study

Delayed diagnosis or misdiagnosis is not uncommon with hereditary angioedema (HAE), especially during pregnancy and the postpartum period. A case study by Canadian authors illustrates that HAE should be considered in the differential diagnosis for any patient with unexplained abdominal pain and recurrent swellings without the presence of urticaria.

Source: Hereditary Angioedema 8. 12. 2022

News You can confirm or exclude ATTRv amyloidosis through genetic testing

Source: Rare Diseases 16. 3. 2022

Články časopisu Prevention of the invasion of malignant cells of gynecologic tumors during surgery

Author of the article: J. Kobilková, J. E. Jirásek, J. Jedličková, O. Benešová, J. Mašata Source: Česká gynekologie | 6/2010 20. 12. 2010

Články časopisu Implementation and applications of robotic surgery within gynecologic oncology and gynecology; analysis of the first thousand cases

Author of the article: C. Lönnerfors, J. Persson Source: Česká gynekologie | 1/2013 1. 3. 2013

Články časopisu Highly active antiretroviral therapy during gestation: effects on a rat model of pregnancy

Author of the article: L. P. Carvalho, R. S. Simões, Edward Araujo Júnior, Oliveira Filho R. M., L. Kulay Júnior, M. U. Nakamura Source: Česká gynekologie | 2/2014 21. 4. 2014

News Metamizole in perioperative treatment in children under 14 years –⁠ results of a questionnaire survey from practice

A recent survey among German-speaking physicians evaluated the use of non-opioid analgesics in perioperative care in children under 14 years. It focused on the use of metamizole and the monitoring of possible agranulocytosis associated with this drug.

Source: Analgesia 17. 3. 2020

News Monocyte Distribution Width as a New Indicator of Sepsis in High-Risk Patients

Most septic patients are first encountered in the emergency department, where sepsis detection is often delayed, partly due to a lack of effective biomarkers. The study presented below evaluated the diagnostic accuracy of monocyte distribution width in peripheral blood alone and in combination with white blood cell count evaluation for early sepsis detection.

Source: Because 13. 9. 2021

News Psychotic patient with high cardiometabolic risk –⁠ interactive case report

The following case report describes the treatment of a patient diagnosed with paranoid schizophrenia following a relapse of the disease. During therapy, complications arose in the form of weight gain, deterioration of metabolic parameters, sedation, and sexual dysfunction. Additionally, the patient is not capable of adhering to the principles of a healthy lifestyle. Is it possible to find an optimal treatment approach even in such a case?

Source: Modern Treatment of Schizophrenia 9. 12. 2021

News Erlotinib in Conditions of Routine Clinical Practice

The patient population in clinical trials is always somewhat selected. Only a well-conducted analysis of real-world clinical practice data can provide a clearer picture of the efficacy and safety of a drug. Therefore, we are currently witnessing a significant development in this type of clinical research, for example, in the form of nationwide cohort studies. How did erlotinib perform in one of them for the treatment of non-small cell lung cancer?

Source: Oncological Treatment 18. 5. 2022

News The role of the physiotherapist in hemophilia care is expanding and irreplaceable −⁠ what it entails and how it changes with treatment advances?

In the team cooperation in caring for patients with hemophilia, the physiotherapist plays a very important role, which is expanding with today's comprehensive approach to treating this condition. The reason is that even in the era of modern treatment availability, many hemophilia patients have various musculoskeletal complications. A team of authors, preferentially physiotherapists, recently published a paper pondering whether the advent of new drugs will also change the position of physiotherapy in the care of patients with hemophilia.

Source: Hemophilia with Movement 21. 11. 2022

News Benefits of Physical Activity for Individuals with Hemophilia –⁠ Recommendations of the MEMO Group

Regular physical activity can increase joint stability and function in individuals with hemophilia, reduce the risk of injury, improve quality of life, and have other positive effects. However, according to recent findings, a regular exercise program is not sufficiently emphasized in comprehensive hemophilia therapy. Therefore, a group of Italian experts has created a consensus summarizing current knowledge about the benefits of exercise for individuals with hemophilia and recommendations for physical activity.

Source: Hemophilia with Movement 25. 11. 2022

News Physiotherapy as Part of Comprehensive Care for People with Hemophilia –⁠ Recommendations vs. Reality

It appears that the physiotherapeutic care provided in reality to people with hemophilia does not align with current recommendations, which see it as an integral part of a multidisciplinary approach. Therefore, in the summer of 2020, an initiative of experts from various countries, including the Czech Republic, was formed to address this issue.

Source: Hemophilia with Movement 30. 11. 2020

Články časopisu Why do we still hesitate to accept the new international criteria for the diagnosis of gestational diabetes mellitus?
The current screening is non-uniform and does not correspondwith evidence-based medicine

Author of the article: Hana Krejčí, Kateřina Anderlová Source: Česká gynekologie | 3/2014 18. 6. 2014

News What is the significance of hormones in the pathophysiology of migraine?

Migraine is a complex neurovascular disease characterized by the dysfunction of the nociceptive trigeminovascular system in its pathophysiology. Its prevalence is 2-3 times higher in women than in men. The cause of this difference has not yet been fully elucidated, but it appears that the fluctuation of ovarian hormone levels and its influence on CGRP plays an important role. The following article summarizes findings on the hormonal influence of migraine and also discusses new prophylactic drugs –⁠ anti-CGRP antibodies.

Source: Migraine 27. 7. 2020