Functional and oncological outcomes after radical cystectomy and orthotopic neobladder in women

Authors: M. H. Zahran;  B. Ali- el- dein
Published in: Urol List 2014; 12(2): 45-51


The trend over the last two decades was toward the use of continent urinary diversion after radical cystectomy in women. The encouraging results of orthotopic neobladder (ONB) in men and the proved oncological and functional safety in early studies in women were behind the application of ONB in women. Many articles have been published in the last two decades concerning the outcome of ONB in women. In this mini‑review, the results of all the available literature concerning this issue and the impact of this surgery on the quality of life are discussed. The results showed lower incidence of local urethral recur­rence in women than in men with the same operation. Day-  and night- time continence in women was achieved in 57– 100% and 27– 92%, respectively. Chronic urinary retention and the use of clean intermit­tent catheterization were much higher in female patients. Sexual function was less affected in women after ONB than those with other forms of urinary diversion. Therefore, ONB should be the first option for females with bladder cancer as long as there is no absolute indication of concomitant urethrectomy.

Key words:
radical cystectomy, orthotopic diversion, results and complications, sexual function


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