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Assessment of liver and its rezidual functional capacity after an extensive resection


Authors: M. Havel 1,2;  A. Vašura 3;  V. Dedek 1,2;  P. Širůček 1,2;  O. Kraft 1,2;  G. Havlová 1;  P. Vávra 4;  M. Vávrová 5;  S. Bobková 1;  K. Trulíková 1
Authors‘ workplace: Klinika nukleární medicíny, Fakultní nemocnice Ostrava 1;  Katedra zobrazovacích metod, Lékařská fakulta Ostravské univerzity 2;  Interní a kardiologická klinika, Fakultní nemocnice Ostrava 3;  Chirurgická klinika, Fakultní nemocnice Ostrava a Lékařská fakulta Ostravské univerzity 4;  Radiodiagnostický ústav, Fakultní nemocnice Ostrava, ČR 5
Published in: NuklMed 2023;12:2-8
Category: Review Article

Overview

Introduction: Extensive resections in liver parenchyma can lead to the liver dysfunction or liver failure due to the insufficient postoperative remnant. Indication process involves direct and indirect methods for the assessment of liver function.

Topic solved: Morphological imaging methods estimate the liver remnant function mainly based on the volume calculations. Laboratory tests asses rather global function and they may not always correlate with the patient’s prognosis. Scintigraphic methods include monitoring of accumulation of iminodiacetic acid derivatives (IDA), especially determination of hepatic extraction fraction (HEF) and calculation of IDA uptake rate in liver parenchyma.

Conclusion: Scintigraphic methods can be used for the estimation of the liver remnant function during the indication for the extensive liver resections. Especially the calculation of IDA uptake rate in liver parenchyma is potent to identify patients in a higher risk of future liver failure.

Keywords:

function – resection – scintigraphy – liver – IDA


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