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Serum concentration and tubular resorption of sodium and chloride in patients with chronic renal disease


Authors: Otto Schück 1,2;  Miroslava Horáčková 1;  Vladimír Teplan 2;  Hana Malinská 2;  Milena Štolová 2;  Irena Látová 2;  Jana Urbanová 2
Authors‘ workplace: Interní klinika 2. LF UK, Praha 1;  Institut klinické a experimentální medicíny, Praha 2
Published in: Čas. Lék. čes. 2015; 154: 236-238
Category: Original Article

Overview

Tubular transport of sodium (TNa+) and chloride (TCl) is decreased in patients with chronic kidney disease. The decrease of TCl is relatively lower than that of TNa+. These changes of tubular transport of Na+ and Cl participate on the development of acid base disturbance in patients with chronic kidney disease and with their glomerular filtration rate lower than 0.5 ml/s/1.73 m2.

Keywords:
sodium – chloride – kidney – tubular reabsorption


Sources

1. Nagasha D, Nassar jr AP, Maciel AT, et al. The use of sodium-chloride difference surrogates in the evaluation of metabolic acidosis in critically ill patients. J Crit Care 2010; 25: 525–531.

2. Kurt A, Ecevit A, Ozkiraz S, et al. The use of chloride-sodium ratio in the evaluation of metabolic acidosis in critically ill neonates. Eur J Pediatr 2012; 171: 963–969.

3. Story DA, Morimatsu H, Bellamo R, et al. Strong ions, weak acids and base excess: a simplified Fencl-Stewart approach to clinical acid-base disorders. Br J Anesth 2004; 92: 54–60.

4. Story DA, Tosolini A, Bellamo R, et al. Plasma acid-base changes in chronical renal failure: a Stewart analysis. Int J Artif Organs 2005; 28: 961–965.

5. Fencl V, Leith DE. Stewart’s quantitative acid-base chemistry: Applications in biology and medicine. Respir Physiol 1993; 91: 1–16.

6. Klaboch J, Opatrná S, Matoušovic K, et al. Acid-base balance in peritoneal dialysis patients: a Stewart-Fencl analysis. Renal Failure 2009; 31: 625–632.

7. Havlín J, Matoušovic K, Schück O, et al. Patofyziologie vzniku metabolické acidózy u pacientů se sníženou glomerulární filtrací z hlediska Stewartovy-Fenclovy teorie. Vnitř. Lék. 2009; 55: 97–104.

8. Opatrná S, Matoušovic K, Klaboch J, et al. Importance of serum (Na+) and (Cl–) difference in acid,base classification. Anesth Analg 2010; 111: 243–244.

9. KDIGO 2012 Clinical Practice Guidelines for Evacuation and Management of Chronic Kidney Disease. Kidney Int 2013; Suppl 3: 1–150.

10. Schück O. Examination of kidney function. Boston – Hague – Dordrecht – Lancastrer: Martinus Nijhoff Publishers 1984.

11. White RP, Samson FE. Determination of inulin by use of anthrone. J Lab Clin Med 1954; 43: 475–478.

12. Fencl V, Jabor A, Kazda A, et al. Diagnosis of metabolic acid-base disturbances in critically ill patients. Am J Resp Crit Care Med 2000; 162: 2246–2251.

13. Halperin M, Goldstein MB. Fluid, Electrolyte and Acid Base Physiology 3rd ed. Philadelphia: WB Saunders Comp. 1999.

14. Jabor A a kol. Vnitřní prostředí. Praha: Grada Publishing 2008.

Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management
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