Postoperative recurrence of Crohn’s disease

Authors: Karel Lukáš
Authors‘ workplace: Univerzita Karlova v Praze, 1. lékařská fakulta, IV. interní klinika VFN
Published in: Čas. Lék. čes. 2011; 150: 594-598
Category: Review Articles


Postoperative recurrence of Crohn’s disease of the bowel is the appearance of objective signs – defined endoscopically, radiologically or pathologically. New lesion can be visualized endoscopically within weeks to months after ileal resection and ileocolonic anastomosis in the neoterminal ileum. Risk factors are smoking, bacterial flora, environmental factors, immune response and genetic variants. Immunomodulators or biological agents are effective in the prophylaxis of postoperative recurrence.

Key words:
Crohn’s disease, recurrence, azathioprin, biological agents.


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