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Extracorporeal removal techniques in toxicology: part 2


Authors: Jaroslav Raděj 1,2;  Jan Horák 1,2;  Martin Harazim 1,2;  Martin Matějovič 1,2
Authors‘ workplace: I. interní klinika LF UK a FN Plzeň 1;  Biomedicínské centrum LF UK, Plzeň 2
Published in: Vnitř Lék 2019; 65(6): 425-432
Category: Review

Overview

The second part of the review deals in detail with the diagnostics and treatment of toxic alcohols poisoning and management and indication of extracorporeal removal techniques in intoxication with other drugs, theophylline, valproic acid, metformin and metformin associated lactic acidosis, respectively. The extracorporeal treatment enhances the clearance of the toxin and corrects patient’s metabolic disturbances as well. It is necessary to use this treatment in severe intoxications. Indication of this invasive procedure falls within clinician’s and nephrologist’s competence being advised by a toxicologist. This review could help make fast decisions.

Keywords:

intoxication – overdose – poisoning – extracorporeal treatment


Sources
  1. Alapat PM, Zimmerman JL. Toxicology in the critical care unit. Chest 2008; 133(4): 1006–1013. Dostupné z DOI: <http://dx.doi.org/10.1378/chest.07–1840>.
  2. Bayliss G. Dialysis in the poisoned patient. Hemodial Int 2010; 14(2): 158–167. Dostupné z DOI: <http://dx.doi.org/10.1111/j.1542–4758.2009.00427.x>.
  3. de Pont AC. Extracorporeal treatment of intoxications. Curr Opin Crit Care 2007; 13(6): 668–673. Dostupné z DOI: <http://dx.doi.org/10.1097/MCC.0b013e3282f0febd>.
  4. Klímová D. Hemodialýza v terapii intoxikací. In: Sulková S (ed) et al. Hemodialýza. Maxdorf: Praha 2000: 590–608. ISBN 80–85912–22–8.
  5. Mirrakhimov AE, Barbaryan A, Gray A et al. The Role of Renal Replacement Therapy in the Management of Pharmacologic Poisonings. Int J Nephrol 2016; 2016: 3047329. Dostupné z DOI: <http://dx.doi.org/10.1155/2016/3047329>.
  6. Mokhlesi B, Leikin JB, Murray P et al. Adult toxicology in critical care: Part II: specific poisonings. Chest 2003; 123(3): 897–922. Dostupné z DOI: <http://dx.doi.org/10.1378/chest.123.3.897>.
  7. Zimmerman JL. Poisonings and overdoses in the intensive care unit: general and specific management issues. Crit Care Med 2003; 31(12): 2794–2801. Dostupné z DOI: <http://dx.doi.org/10.1097/01.CCM.0000100123.50896.F0>.
  8. Medscape. WebMD: New York City, New York, USA. Dostupné z WWW: <http://www.medscape.com>.
  9. UpToDate Inc. Evidence-based clinical decision support resource. Wolters Kluwer Health: Waltham, Massachusetts, USA. Dostupné z WWW: <http://www.uptodate.com>.
  10. Kraut JA, Kurtz I. Toxic alcohol ingestions: clinical features, diagnosis, and management. Clin J Am Soc Nephrol 2008; 3(1): 208–225. Dostupné z DOI: <http://dx.doi.org/10.2215/CJN.03220807>.
  11. Kraut JA, Mullins M.E Toxic Alcohols. N Engl J Med 2018; 378(3): 270–280. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJMra1615295>. Erratum in Toxic Alcohols. [N Engl J Med 2019].
  12. Garrard A, Sollee DR, Butterfield RC et al. Validation of a pre-existing formula to calculate the contribution of ethanol to the osmolar gap. Clin Toxicol (Phila) 2012; 50(7): 562–566. Dostupné z DOI: <http://dx.doi.org/10.3109/15563650.2012.704039>.
  13. Purssell RA, Pudek M, Brubacher J et al. Derivation and validation of a formula to calculate the contribution of ethanol to the osmolal gap. Ann Emerg Med 2001; 38(6): 653–659. Dostupné z DOI: <http://dx.doi.org/10.1067/mem.2001.119455>.
  14. Barceloux DG, Bond GR, Krenzelok EP et al. American Academy of Clinical Toxicology Ad Hoc Committee on the Treatment Guidelines for Methanol Poisoning. American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol Clin Toxicol 2002; 40(4): 415–446.
  15. Barceloux DG, Krenzelok EP, Olson K et al. American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee. J Toxicol Clin Toxicol 1999; 37(5): 537–560.
  16. Brent J Fomepizole for ethylene glycol and methanol poisoning. N Engl J Med 2009; 360(21): 2216–2223. Dostupné z DOI: <http://dx.doi.org/10.1056/NEJMct0806112>.
  17. Mégarbane B, Borron SW, Baud FJ. Current recommendations for treatment of severe toxic alcohol poisonings. Intensive Care Med 2005; 31(2): 189–195. Dostupné z DOI: <http://dx.doi.org/10.1007/s00134–004–2521–0>.
  18. Kraut JA. Approach to the Treatment of Methanol Intoxication. Am J Kidney Dis 2016; 68(1): 161–167. Dostupné z DOI: <http://dx.doi.org/10.1053/j.ajkd.2016.02.058>.
  19. Odborné doporučení pro intoxikaci – metanol (methanol, metylalkohol, dřevný líh, CH3OH). Toxikologické informační středisko, Klinika pracovního lékařství VFN a 1. LF UK Praha 2015. Dostupné z WWW: <http://www.tis-cz.cz/images/stories/PDFs/methanol2/METANOL-odborne-doporuceni-TIS-akt-8–2-2015.pdf>.
  20. Roberts DM, Yates C, Megarbane B et al. [EXTRIP Work Group]. Recommendations for the role of extracorporeal treatments in the management of acute methanol poisoning: a systematic review and consensus statement. Crit Care Med 2015; 43(2): 461–472. Dostupné z DOI: <http://dx.doi.org/10.1097/CCM.0000000000000708>.
  21. Hirsch DJ, Jindal KK, Wong P et al. A simple method to estimate the required dialysis time for cases of alcohol poisoning. Kidney Int 2001; 60(5): 2021–2024. Dostupné z DOI: <http://dx.doi.org/10.1046/j.1523–1755.2001.00003.x>.
  22. Zakharov S, Pelclova D, Navratil T et al. Intermittent hemodialysis is superior to continuous veno-venous hemodialysis/hemodiafiltration to eliminate methanol and formate during treatment for methanol poisoning. Kidney Int 2014; 86(1): 199–207. Dostupné z DOI: <http://dx.doi.org/10.1038/ki.2014.60>.
  23. Zakharov S, Rulisek J, Nurieva O et al. Intermittent versus continuous renal replacement therapy in acute methanol poisoning: comparison of clinical effectiveness in mass poisoning outbreaks. Ann Intensive Care 2017; 7(1): 77. <http://dx.doi.org/10.1186/s13613–017–0300–7>.
  24. Odborné doporučení pro intoxikaci – izopropylalkohol (isopropanol, 2-propanol, C3H7OH). Toxikologické informační středisko, Klinika pracovního lékařství VFN a 1. LF UK Praha 2012.
  25. Souhrny údajů o přípravcích. Státní ústav pro kontrolu léčiv: Praha ČR. Dostupné z WWW: <http://www.sukl.cz>.
  26. Calello DP, Liu KD, Wiegand TJ et al. Extracorporeal Treatment for Metformin Poisoning: Systematic Review and Recommendations From the Extracorporeal Treatments in Poisoning Workgroup. Crit Care Med 2015; 43(8): 1716–1730. Dostupné z DOI: <http://dx.doi.org/10.1097/CCM.0000000000001002>.
  27. Regolisti G, Antoniotti R, Fani F et al. Treatment of Metformin Intoxication Complicated by Lactic Acidosis and Acute Kidney Injury: The Role of Prolonged Intermittent Hemodialysis. Am J Kidney Dis 2017; 70(2): 290–296. Dostupné z DOI: <http://dx.doi.org/10.1053/j.ajkd.2016.12.010>.
  28. Ghannoum M, Wiegand TJ, Liu KD et al. Extracorporeal treatment for theophylline poisoning: systematic review and recommendations from the EXTRIP workgroup. Clin Toxicol (Phila) 2015; 53(4): 215–229. Dostupné z DOI: <http://dx.doi.org/10.3109/15563650.2015.1014907>.
  29. Ghannoum M, Laliberté M, Nolin TD et al. Extracorporeal treatment for valproic acid poisoning: systematic review and recommendations from the EXTRIP workgroup. Clin Toxicol (Phila) 2015; 53(5): 454–465. Dostupné z DOI: <http://dx.doi.org/10.3109/15563650.2015>.
Labels
Diabetology Endocrinology Internal medicine
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