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Nutrition in the prevention of Parkinson’s disease


Authors: I. Klimešová 1;  M. Šlachtová 2
Authors‘ workplace: Fakulta tělesné kultury UP v Olomouci ;  Katedra přírodních věd v kinantropologii, Vedoucí: prof. RNDr. Miroslav Janura, Ph. D. 1;  Katedra fyzioterapie, Vedoucí: prof. MUDr. Jaroslav Opavský, CSc. 2
Published in: Prakt. Lék. 2015; 95(4): 167-170
Category: Of different specialties

Overview

Parkinson’s disease (PD) is a chronic neurodegenerative disorder affecting roughly 1% individuals over age of 60 in Europe. Although the exact cause of the disease is not yet known, it is obvious that the food together with a genetic predisposition plays an important role in the development of the disease.

The study summarizes results of researches focused on the preventive effect of nutrition in the development of PD. Despite the fact that the findings of studies are not always consistent, research suggests that high consumption of milk and dairy products is associated with an increased risk of developing PD. This relationship appears stronger for men than for women.

Inversely, nutritional factor that is as protective high intake of vegetables and fruits, specially berries. Furthermore, it is relatively well established protective effect of caffeine intake. The inverse association of caffeine intake in women is not as straightforward as in men but it is U-shaped. Research findings are less consistent about the Parkinson’s preventive benefits of polyunsaturated fatty acids. Studies have demonstrated an association between a Mediterranean diet and Parkinson’s risk. The Mediterranean diet should be not be considered as effective only in preventing cardiovascular disease, but also in delaying PD, as two large prospective study demonstrated.

Therefore, we can assume that diet rich in fish and vegetable products (vegetables and fruits, nuts, legumes, whole grains, olive oil), and inversely low in animal fats, has proven health benefits.

Keywords:
Parkinson’s disease – nutrition – milk – vegetables and fruits – caffeine – Mediterranean diet


Sources

1. Warner TT, Schapira AHV. Genetic and environmental factors in the cause of Parkinson’s disease. Ann Neurol 2003; 53(Suppl 3): 16–23.

2. Miyake Y, Tanaka K, Fukushima W, et al. Lack of association of dairy food, calcium, and vitamin D intake with the risk of Parkinson’s disease: a case-control study in Japan. Parkinsonism Relat Disord 2011; 17(2): 112–116.

3. Chen H, Zhang SM, Hernan MA, et al. Diet and Parkinson’s disease: a potential role of dairy products in men. Ann Neurol 2002; 52: 793–801.

4. Park M, Ross GW, Petrovitch H, et al. Consumption of milk and calcium in midlife and the future risk of Parkinson disease. Neurology 2005; 64: 1047–1051.

5. Kyrozis A, Ghika A, Stathopoulos P, et al. Dietary and lifestyle variables in relation to incidence of Parkinson’s disease in Greece. Eur J Epidemiol 2013; 28: 67–77.

6. Chen H, O’Reilly E, McCullough ML, et al. Consumption of dairy products and risk of Parkinson’s disease. Am J Epidemiol 2007; 165: 998–1006.

7. Choi HK, Liu S, Curhan G. Intake of purine-rich foods, protein, and dairy products and relationship to serum levels of uric acid: the Third National Health and Nutrition Examination Survey. Arthritis Rheum 2005; 52: 283–289.

8. Shen C, Guo Y, Luo W, et al. Serum urate and the risk of Parkinson’s disease: results from a meta-analysis. Can J Neurol Sci 2012; 88: 73–79.

9. Seidl SE, Santiago JA, Bilyk H, Potashkin JA. The emerging role of nutrition in Parkinson’s disease. Front Aging Neurosci 2014; 6: 36.

10. Pandey KB, Rizvi SI. Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev 2009; 2(5): 270–278.

11. Subash S, Essa MM, Al-Adawi S, et al. Neuroprotective effects of berry fruits on neurodegenerative diseases. Neural Regen Res 2014; 9(16): 1557–1566.

12. Rendeiro C, Guerreiro JD, Williams CM, Spencer JP. Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects. Proc Nutr Soc 2012; 71: 246–262.

13. Youdim KA, Joseph JA. A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects. Free Radic Biol Med 2001; 30: 583–594.

14. Chen L, Xin X, Zhang H, Yuon Q. Phytochemical properties and antioxidant capacities of commercial raspberry varieties. J Funct Foods 2013; 5: 508–515.

15. Rios de Souza V, Pimenta Pereira PA, Teodoro da Silva TL, de Oliveira Lima LC, et al. Determination of the bioactive compounds, antioxidant activity and chemical composition of Brazilian blackberry, red raspberry, strawberry, blueberry and sweet cherry fruits. Food Chem 2014; 156: 362–368.

16. Tavares L, Figueira I, McDougall GJ, et al. Neuroprotective effects of digested polyphenols from wild blackberry species. Eur J Nutr 2013; 52(1): 225–236.

17. Kaur H, Chauhan S, Sandhir R. Protective effect of lycopene on oxidative stress and cognitive decline in roten one induced model of Parkinson’s disease. Neurochem Res 2011; 36: 1435–1443.

18. Miyake Y, Fukushima W, Tanaka K, et al. Dietary intake of antioxidant vitamins and risk of Parkinson’s disease: a case-control study in Japan. Eur J Neurol 2011; 18: 106–113.

19. Murakami K, Miyake Y, Sasaki S, et al. Dietary intake of folate, vitamin B6, vitamin B12 and riboflavin and risk of Parkinson’s disease: a case-control study in Japan. Br J Nutr 2010; 104: 757–764.

20. Abbott RD, Ross GW, WhiteLR, et al. Environmental, life-style, and physical precursors of clinical Parkinson’s disease: recent findings from the Honolulu-Asia aging study. J Neurol 2003; 250(Suppl 3): III30–III39.

21. Agim ZS, Cannon JR. Dietary factors in the etiology of Parkinson’s disease. Biomed Res Int 2015; 2015: 672838. doi:10.1155/2015/672838.

22. Ross GW, Abbott RD, Petrovitch H, et al. Association of coffee and caffeine intake with the risk of Parkinson disease. JAMA 2000; 283(20): 2674–2679.

23. Hernán MA, Takkouche B, Caamaño-Isorna F, Gestal-Otero JJ. A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson’s disease. Ann Neurol 2002; 52(3): 276–284.

24. Palacios N, Gao X, McCullough ML, et al. Caffeine and risk of Parkinson disease in a large cohort of men and women. Mov Disord 2013; 27(10): 1276–1282.

25. Ascherio A, Weisskopf MG, O’Reilly EJ, et al. Coffee consumption, gender, and Parkinson’s disease mortality in the Cancer Prevention Study-II cohort: the modifying effects of estrogen. Am J Epidemiol 2004; 160(10): 977–984.

26. Trevitt J, Kawa K, Jalali A, Larsen C. Differential effects of adenosine antagonists in two models of Parkinsonian tremor. Pharmacol Biochem Behav 2009; 94: 24–29.

27. Kitagawa M, Houzen H, Tashiro K. Effects of caffeine on the freezing of gait in Parkinson’s disease, Mov Disord 2007; 22: 710–712.

28. Zeynep S, Agim JRC. Dietary factors in the etiology of Parkinson’s disease. Biomed Res Int 2015; 2015: 469–478.

29. Chen H, Zhang SM, Hernán M, et al. Dietary intakes of fat and risk of Parkinson’s disease. Am J Epidemiol 2003; 157(11): 1007–1014.

30. Dong J, Beard JD, Umbach DM, et al. Dietary fat intake and risk for Parkinson’s disease. Movement Disorders 2014; 29(13): 1623–1630.

31. Singh RB, Dubnov G, Niaz MA, et al. Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial. Lancet 2002; 360: 1455–1461.

32. Trichopoulou A, Lagiou P, Kuper H, Trichopoulos D. Cancer and Mediterranean dietary traditions. Cancer Epidemiol Biomarkers Prev 2000; 9: 869–873.

33. Trichopoulou A, Costacou T, Bamia C, Trichopoulos D. Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med 2003; 348: 2599–2608.

34. Scarmeas N, Stern Y, Tang MX, et al. Mediterranean diet and risk for Alzheimer’s disease. Ann Neurol 2006; 59: 912–921.

35. Gao X, Chen H, Fung TT, et al. Prospective study of dietary pattern and risk of Parkinson disease. Am J Clin Nutr 2007; 86: 1486–1494.

36. Alcalay RN, Gu Y, Mejia-Santana H, et al. The association between Mediterranean diet adherence and Parkinson‘s disease. Mov Disord 2012; 27(6): 771–774.

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