Twenty five years since the discovery of the human immunodeficiency virus (HIV)
Authors:
M. Staňková 1; V. Skokanová 2
Authors‘ workplace:
AIDS centrum FN Na Bulovce, Praha
III. klinika infekčních a tropických nemocí 1. LF UK, Praha
Vedoucí lékař: doc. MUDr. Marie Staňková, CSc.
1; Laboratoř lékařské mikrobiologie a imunologie, Praha
Zdravotní ústav se sídlem v Kolíně
Vedoucí lékař: MUDr. Venuše Skokanová, CSc.
2
Published in:
Prakt. Lék. 2008; 88(11): 627-629
Category:
Editorial
Overview
The article reminds the twenty fifth anniversary of discovery of the etiological agent of the acquired immunodeficiency syndrome (AIDS) - the human immunodeficiency virus (HIV). It surveys retrospectively several periods in the field of molecular virology and HIV infection epidemiology, and closely related therapeutic procedures. UNAIDS WHO facts clearly document that the catastrophic pandemic is by far not solved and its spread, mainly in developing countries is a global challenge for the entire world. Numbers of HIV/AIDS patients in the Czech Republic are so far low, the care is concentred into regional AIDS centres. However, even in our country an important increase in HIV infected persons is observed in past two years, which reflects global trends in the world. The pandemic of AIDS cannot be mastered without adequate preventive measures, where a support of the state plays an important role, sufficient financial resources, and an international cooperation.
Key words:
human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), antiretroviral therapy, preventive measures.
Sources
1. Argyris, E.G., Acheampong,E., Fengxiang W., et al. The interferon-induced expression of APOBEC3G in human blood-brain barier exerts a potent intrinsic imunity to block HIV-1 entry to central nervous system. Virology, 2007, 367/2, p. 440-451.
2. Barre-Sinoussi, F., Cherman, J.C., Rey, F., et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immunodeficiency syndrome (AIDS). Science,1983, 220, p.868-871.
3. Clavel, F., Guetard, D., Brun-Vezinet,F.,et al. Isolation of a new human retrovirus from West African patients with AIDS. Science, 1986, 233, p. 343-346.
4. Conner, E.M., Sperling, R.S., Gerber, R., et al.. Reduction of Materna-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N. Engl. J. Med. 1994, 331, p. 1173-1180.
5. Doolittle, R.F.. Immunodeficiency viruses: the simian-human connection. Nature 1989, 339, p. 338-9.
6. Fauci, A.S. 25 years of HIV. Nature 2008, 453, p. 289-290.
7. Gallo, R.C. Historical essay. The early years of HIV/AIDS. Science 2002, 298, p.1728-1730.
8. Gao, F., Bailes, E., Robertson, D.L., et al.. Origin of HIV-1 in Pan troglodytes troglodytes. Nature 1999, 397(6718), p. 436-441.
9. Gottlieb, M.S., Schroff, R., Schanker, H.M., et al. Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency. N. Engl. J. Med. 1981, 305, p. 1425-1431.
10. Montagnier, L. Historical essay. The early years of HIV/AIDS. Science 2002, 298, p.1727-1728.
11. Sedláček, D., Staňková, M., Machala, L. et al. Komplexní postup antiretrovirové léčby osob infikovaných virem lidské imunodeficience (HIV) v České republice. Klin. Mikrobiol. Inf. Lék. 2007, 13(1), s. 28-34.
12. Staňková, M., Skokanová, V. Problematika HIV/AIDS - ohlédnutí a perspektivy. Klin. Mikrobiol. Inf. Lék. 2004, 10(2), s. 56-60.
13. Staňková, M., Skokanová, V. Historie a perspektivy antiretrovirové terapie infekce HIV/AIDS. Remed, 2007, 17(2), s. 175-180.
14. SZÚ Praha. Národní referenční laboratoř pro AIDS: HIV pozitivní případy v ČR k 31. 7. 2008.
15. Tuofu, Z., Korber, B., Nahinias, A.J. An African HIV - Sequence from 1959 and implications for the origin of the epidemic. Nature 1998, 391, p. 594.
Labels
General practitioner for children and adolescents General practitioner for adultsArticle was published in
General Practitioner
2008 Issue 11
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