Endoscopic ultrasound-guided ethanol ablation of pancreatic cystic neoplasia


Authors: M. Kliment 1;  O. Urban 1,2;  D. Žiak 3;  P. Fojtík 1;  P. Falt 1;  J. Dvořáčková 2,4
Authors‘ workplace: Centrum péče o zažívací trakt, Vítkovická nemocnice a. s., Ostrava, 2Lékařská fakulta ostravské univerzity, Ostrava, 3CGB Laboratoř, Patologie, Ostrava, 4Patologie, Fakultní nemocnice Ostrava 1
Published in: Gastroent Hepatol 2012; 66(3): 183-186
Category: Digestive Endoscopy: Video-Case Report

Overview

Endoscopic ultrasound-guided ethanol ablation/lavage of pancreatic cystic neoplasia is a new method of local ablative treatment, when highly concentrated ethylalcohol is injected into the cyst. The principle of the method is the chemical lysis of neoplastic cells in inner lining of the cyst with subsequent regression of cystic neoplasia. Recently, the method has been used mostly in clinical trials, that have confirmed efficacy in 33–79%. The authors present a video-case report of an older patient with significant comorbidities and pancreatic cystic neoplasia, that was treated by ethanol ablation. The authors discuss hitherto published papers dealing with EUS-guided ethanol ablation of pancreatic cysts, especially the efficacy and safety of the method.

Key words:
endosonography – endoscopic ultrasound-guided ethanol ablation – ethanol lavage – pancreatic cystic neoplasia


Sources

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9. Matthes K, Mino-Kenudson M, Sahani DV et al. Concentration-dependent ablation of pancreatic tissue by EUS-guided ethanol injection. Gastrointest Endosc 2007; 65(2): 272–277.

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Labels
Paediatric gastroenterology Gastroenterology and hepatology Surgery

Article was published in

Gastroenterology and Hepatology

Issue 3

2012 Issue 3

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