Autoimmune pancreatitis in a patient with Crohn’s disease

Authors: P. Klvaňa;  O. Urban;  A. Martínek;  E. Machytka;  P. Svoboda
Authors‘ workplace: Interní klinika, FN Ostrava a LF Ostravské univerzity
Published in: Gastroent Hepatol 2011; 65(4): 211-214
Category: Clinical and Experimental Gastroenterology: Case Report


Autoimmune pancreatitis (AIP) represents a rare form of chronic pancreatitis, which can be associated with other autoimmune diseases. In 20–30% of patients with ductocentric AIP, concurrent inflammatory bowel diseases (IBD), more frequently ulcerative colitis (UC), are described. This finding can mimic a malignant tumour of the pancreas and was incorrectly indicated for surgical therapy in the past. Very good response to corticosteroids therapy is characteristic feature for this type of AIP. The authors reported a case of a 37-year old woman with Crohn’s disease in whom ductocentric AIP was diagnosed with good and prompt response to corticosteroids therapy.

Key words:
autoimmune pancreatitis – Crohn’s disease – endoscopic ultrasound


1. Yoshida K, Toki F, Takeuchi TA et al. Chronic pankreatitis caused by an autoimmune abnormality. Proposal of the concept of autoimmune pankreatitis Dog Dis Sci 1995; 40(70): 1561–1568.

2. Dítě P, Ševčíková A, Novotný I et al. Auto­imunní pankreatitida v ČR – region jižní Morava (doplnit citaci). Čes a Slov Gastroent a Hepatol 2007; 61(2): 82–85.

3. Novotný I, Dítě P, Lata et al. Autoimmune Pancreatitis – Recent Advances. Dig Dis 2010; 28(2): 334–338.

4. Dítě P, Novotný I, Kinkor Z et al. Auto­imunní forma chronické pankreatitidy a IgG4 pozitivní mastitida. Gastroent He­patol 2011; 65(1): 22–25.

5. Frulloni L, Scatollini Ch, Katsotourchi AM et al. Exocrine and endocrine Pan­creatic Function in 21 Patients Suffering from Auto­immune Pancreatitis before and after Steroid Treatment. Pancreatology 2010; 10(2–3): 129–133.

6. Kamisawa T, Yoshiike M, Egawa N et al. Treating Patients with Autoimmune Pancreatitis : Results from a Lomg-Term Follow-Up Study. Pancreatology 2005; 5(2–3): 234–224.

7. Saito T, Tanaka S, Yoshida H et al. A Case of Autoimmune Pancreatitis Responding to Steroid Therapy. Evidence of Histo­logic Recovery. Pancreatology 2002; 2(6): 550–555.

8. Kamisawa T, Notohara K, Shimosegawa T. Two Clinicopathologic Subtypes of Autoimmune Pancreatitis LPSP and IDCP. Gastroenterology 2010; 139(1): 22–25.

9. Chari ST, Kloeppel G, Zhang L et al. for the Autoimmune Pancreatitis Internationale Cooperative Study Group. Histopathologic and Clinical Subtypes of Autommune Pancreatitis: The Honolulu Consensus Document Pancreatology 2010; 10: 664–672.

10. Kamisawa T, Yoshiike M, Egawa N et al. Chronic Pancreatitis in the Elderly in Japan. Pancreatology 2004; 4(3–4): 223–228.

11. Otsuki M. Chronic Pancreatitis. The Problems of Diagnostic Criteria. Pancreatology 2004; 4(1): 28–41.

12. Kliment M, Urban O, Čegan M et al. ­Endoscopic ultrasound-guided fine needle ­aspiration of pancreatic masses: the utility and impact on management of patients, Scand. Journal of Gastroenterology 2010; 45(11), 1372–1379.

13. Ravi K, Chari ST, Vege SS et al. Inflammatory bowel disease in the petting of auto­immune pancreatitis. Inflamm Bowel Dis 2009; 15(9): 1326–1330.

14. Chari ST. Diagnosis of autoimmune pancreatitis using its five cardinal features: introducing the Mayo Clinic´s HISORt criteria. J Gastroenterol 2007; 42(SupplXVIII); 39–41.

Paediatric gastroenterology Gastroenterology and hepatology Surgery

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