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Combined x-ray and Microscopic Examination of Nonpalpable Breast Lesionswith Calcifications


Authors: M. Podhola 1;  H. Urmínská 2
Authors‘ workplace: Fingerlandův ústav patologie, Fakultní nemocnice, Hradec Králové 2Radiologická klinika, Fakultní nemocnice, Hradec Králové 1
Published in: Čes.-slov. Patol., , 2004, No. 1, p. 12-17
Category:

Overview

Radiograms of nonpalpable breast lesions containing calcifications represent one of the mostimportant fields of using x-ray in breast pathology. An analysis of a group of 52 nonpalpablelesions of breast with calcifications revealed a discrepancy between the presence of calcificationsin radiograms and in histological sections. An absence of calcifications was observed in 47 of 301(15.7%) paraffin blocks. Calcifications were lost by cutting them off from the blocks, by leavingthem deeper in blocks so that they were absent in sections, or by losing them by various otherways during processing of the blocks. An algorithm for examination of nonpalpable calcifiedlesions of breast has been developed. During the procedure, tissue slices and paraffin block werex-rayed, thus increasing the detection of calcifications in blocks from 76 % to 84.3 %.

Key words:
specimen radiography - breast - calcifications - paraffin blocks

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Labels
Anatomical pathology Forensic medical examiner Toxicology
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