Structural Correlations of Splenic Tissue in Idiopathic ThrombocytopenicPurpura of Adults (ITP)

Authors: Jirásek A. () 1;  Salaj P. () 1;  Vorlová Z. () 1;  Kolářová M. () 2
Authors‘ workplace: (1) Ústav hematologie a krevní transfuze, Praha, ředitel MUDr. RNDr. P. Jarolím, DrSc. (2) Hlavův I. patologickoanatomický ústav 1. LF UK, Praha, přednosta prof. MUDr. P. Miřejovský, DrSc.
Published in: Čes.-slov. Patol., , 1999, No. 2, p. 45-54


Immunologic activation of the splenic white pulp seemed to be an important feature of thestructural changes in the 8 splenectomized patients with ITP. However, destruction of the plate-lets with CD 16+ monocytes was the most prominent change in the Billroth’s cords of the splenicred pulp. Classical NK cells did not play an important role in platelets destruction.

Key words:
idiopathic thrombocytopenic purpura - splenic pulp - monocytes

Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP.

Anatomical pathology Forensic medical examiner Toxicology
Forgotten password

Don‘t have an account?  Create new account

Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.


Don‘t have an account?  Create new account