Structural Correlations of Splenic Tissue in Idiopathic ThrombocytopenicPurpura of Adults (ITP)

Czech version

Authors: Jirásek A. () ¹; Salaj P. () ¹; Vorlová Z. () ¹; Kolářová M. () ²
Authors‘ workplace: (1) Ústav hematologie a krevní transfuze, Praha, ředitel MUDr. RNDr. P. Jarolím, DrSc. (2) Hlavův I. patologickoanatomický ústav 1. LF UK, Praha, přednosta prof. MUDr. P. Miřejovský, DrSc.
Published in: Čes.-slov. Patol., , 1999, No. 2, p. 45-54
Category:

Overview

Immunologic activation of the splenic white pulp seemed to be an important feature of thestructural changes in the 8 splenectomized patients with ITP. However, destruction of the plate-lets with CD 16+ monocytes was the most prominent change in the Billroth’s cords of the splenicred pulp. Classical NK cells did not play an important role in platelets destruction.

Key words:
idiopathic thrombocytopenic purpura - splenic pulp - monocytes

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Article was published in

Czecho-Slovak Pathology

1999 Issue 2