It is never too late – HSV1-induced herepetic encephalitis

Authors: E. Dická 1;  Z. Pavlovičová 2;  Ľ. Podracká 1
Authors‘ workplace: Detská klinika LFUK a NÚDCH, Bratislava, Slovensko 1;  Rádiodiagnostické oddelenie NÚDCH, Bratislava, Slovensko 2
Published in: Čes-slov Pediat 2020; 75 (1): 34-39.
Category: Case Report


Herpetic encephalitis is the most prevalent sporadic fatal encephalitis in the world. The disease affects all age groups. The gold standard of diagnosis is the investigation of viral load in cerebrospinal fluid and the magnetic resonance imaging of the brain. Intravenous treatment with acyclovir is initiated immediately upon suspicion of herpes encephalitis. The recommended treatment duration is 21 days. Prior to therapy discontinuation, repeated lumbar punctures are recommended to confirm negative viral load by polymerase chain reaction.

In the article we demonstrate two case reports of herpetic encephalitis with different clinical course and prognosis.


herpetic encephalitis – lumbar puncture – acyclovir treatment


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Neonatology Paediatrics General practitioner for children and adolescents
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