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TB meningitis in the Czech Republic – new encounter with an old diagnosis after 20 years


Authors: T. Čábelová 1;  V. Dedek 1;  P. Kabíček 1;  K. Křepela 1;  Z. Rýznarová 2;  I. Pospíšilová 3;  H. Houšťková 1
Authors‘ workplace: Pediatrická klinika IPVZ, 1. LF UK a Thomayerova nemocnice, Praha, přednostka doc. MUDr. H. Houšťková, CSc. 1;  Radiodiagnostické oddělení, Thomayerova nemocnice, Praha, primářka MUDr. J. Votrubová, CSc. 2;  Oddělení klinické biochemie, Thomayerova nemocnice, Praha, primářka MUDr. K. Bořecká. 3
Published in: Čes-slov Pediat 2016; 71 (7-8): 345-350.
Category: Tuberculosis

Kazuistiky byly předneseny 15. 10. 2015 na 10. česko-slovenském kongresu dětské anestezie a intenzivní medicíny.

Overview

Authors present three pediatric cases of tuberculous meningitis treated in their department since 2013. Symptoms, laboratory and imaging results, therapy and current clinical state of the patients are discussed.

Key words:
tuberculous meningitis, TBC, vasculitis, hydrocephalus, salt wasting syndrome, coefficient of energy balance.


Sources

1. Karsen H, Koruk ST, Karahocagil MK, et al. Comparative analysis of cerebrospinal fluid adenosine deaminase activity in meningitis. Swiss Med Wkly 2011 Jun 24; 141: w13214. Epub 2011 Jun 24.

2. Thwaites GE, Nguyen Duc Bang. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med 2004; 351: 1741–1751.

3. Donald PR, Van Toorn R. Use of corticosteroids in tuberculous meningitis, Lancet 2016 Jun 25; 387 (10038): 2585–2587. doi: 10.1016/S0140-6736(16)30770-X.

4. Thwaites GE, Toorn R, Schoeman J. Tuberculous meningitis: more questions, still too few answers. Lancet Neurol 2013, 12: 999–1010.

5. Křepela K. Tuberkulóza dětí a dorostu a její diferenciální diagnostika. Praha: Maxdorf, 1995. ISBN 80-85912-03-1.

6. Ho J, Marais BJ, Gilbert GL, et al. Diagnosis tuberculous meningitis – have we made any progress? Trop Med Int Health 2013 June; 18 (6): 783–793.

7. Celik U, Celik T, Tolunay O, et al. Cerebral salt wasting in tuberculous meningitis: Two cases and review of the literature. Case report. Neuro Endocrinol Lett 2015; 36 (4): 306–310.

8. Rohlwink UK, Kilborn T, Wieselthaler N, et al. Imaging features of the brain, cerebral vessels and spine in pediatric tuberculous meningitis with associated hydrocefalus. Pediatr Infect Dis J 2016 Oct; 35 (10): e301–310.

Labels
Neonatology Paediatrics General practitioner for children and adolescents
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