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Amelanotic and Acrolentiginous Melanoma


Authors: N. Vojáčková;  R. Schmiedbergerová;  J. Hercogová
Authors‘ workplace: Dermatovenerologická klinika UK 2. LF a FN Na Bulovce přednostka prof. MUDr. Jana Hercogová, CSc.
Published in: Čes-slov Derm, 83, 2008, No. 2, p. 77-80
Category: Case Reports

Overview

The case study describes a 67-year-old patient with two primary melanomas on the back and on the lateral side of the left foot, histopathologically diagnosed as amelanotic and acrolentiginous type, respectively. The second lesion was diagnosed during follow-up seven months after excision of the first tumor. Family history of melanoma was negative and no multiple atypical nevi were present in this patient.

Incidence of multiple melanoma ranges from 0.5 to 5.5 % or 1.3 to 8% in different reviews. The risk factors include positive family history, multiple dysplastic nevi, increasing Breslow depth of invasion of the first melanoma, male sex, another tumor in personal history.

Number of reviews deal with the contribution of follow-up in melanoma patients, follow-up frequency and extensity of examination. Some authors proved that due to follow-up the second melanoma is detected in earlier stages and thus with better prognosis.

Key words:
amelanotic melanoma – acrolentiginous melanoma – follow-up


Sources

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2. CONRAD, N., LEIS, P., ORENGO, I. et al. Multiple primary melanoma. Derm Surg, 1999, 25, p. 576–581.

3. DIFRONZO, LA., WANEK, LA., MORTON, DL. Earlier diagnosis of second primary melanoma confirms the benefits of patient education and routine postoperative follow-up. Cancer, 2001, 15, p. 1520–1524.

4. DIFRONZO, LA., WANEK, LA., ELASHOFF, R., MORTON, DL. Increased incidence of second primary melanoma in patients with a previous cutaneous melanoma. Ann Surg Oncol, 1999, 6 (7), p. 705–711.

5. FERRONE, CL., BEN, PL., PANAGEAS, KS. et al. Clinicopathological features of and risk factors for multiple primary melanomas. JAMA, 2005, 294 (13), p. 1647–1654.

6. GARBE, C., PAUL, A., KOHLER-SPATH, H. et al. Prospective evaluation of a follow-up schedule in cutaneous melanoma patients: recommendations for an effective follow-up strategy. J Clin Oncol, 2003, 21 (3), p. 520-529.

7. GOLDBERG, MS., DOUCETTE, JT., LIM, WH. Et al. Risk factors for presumptive melanoma in skin cancer screening: American Academy of Dermatology National Melanoma/Skin Cancer Screening Program Experience 2001–2005. J Am Acad Dermat, 2007, 57 (1), p. 60–66.

8. POO-HWU, WJ., ARIYAN, S., LAMB, L. et al. Follow-up recommendations for patients with American Joint Committee on Cancer stages I-III malignant melanoma. 1999, Cancer, 86 (11), p. 2252-2258.

9. SAVOIA, P., QUAGLINO, P., VERRONE, A. et al. Multiple primary melanomas: analysis of 49 cases. Mel Res, 1998, 8 (4), p. 361–366.

10. SLINGLUFF, CL., VOLLMER, RT., SEIGLER, HF. Multiple primary melanoma: incidence and risk factors in 283 patients. Surgery, 1993, 113 (3), p. 330–339.

11. SHAPIRO, MA. Five primary disparate melanomas: a case report (the spectrum of melanoma). J Derm Surg Oncol, 1988, 14 (12), p. 1378–1385.

Labels
Dermatology & STDs Paediatric dermatology & STDs
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