Porokeratosis Superficialis Disseminata Actinica, Tacalcitol Treatment

Authors: V. Miňovská;  P. Zloský
Authors‘ workplace: Dermatovenerologická klinika 1. LF UK, VFN Praha
Published in: Čes-slov Derm, , 2000, No. 4, p. 156-158


Disseminated superficial actinic porokeratosis is manifested in the third and fourth decade oflife by multiple brownish annular keratotic foci mainly on the extensor surfaces of the lowerextremities and arms. A typical feature is the histological picture of cornoid lamella. Association ofthe disease with UV radiation or with immunosusuppression is known as well as a tendency ofdevelopment of malignity. Treatment remains a problem. The authors investigated the response ofporokeratotic lesions to the local application of tacalcitol. After a three-month follow-up the pruritusdisappeared and some of the manifestations were paler, while some 50 % foci did not respond totreatment. Long-term experience is needed before final conclusions can be made.

Key words:
porokeratosis superficialis disseminata actinica - tacalcitol

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Dermatology & STDs Paediatric dermatology & STDs
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