Treatment of rheumatoid arthritis and the liver

Authors: S. Fraňková;  J. Šperl;  J. Špičák
Authors‘ workplace: Klinika hepatogastroenterologie, Institut klinické a experimentální medicíny, Praha
Published in: Čes. Revmatol., 18, 2010, No. 3, p. 112-118.
Category: Overview Reports


A review of liver diseases which are commonly associated with rheumatoid arthritis is presented. In adults, liver steatosis, autoimmune hepatitis, primary biliary cirrhosis and hepatitis B reactivation and recurrence are frequently encountered. Basic differential diagnosis of these medical conditions and their therapy is discussed. A drug-induced liver injury is also frequent in patients with rheumatoid arthritis. We define the drug-induced liver injury and its classification, and further, we discuss differential diagnosis, ethiology and mechanism of toxicity of drugs used in rheumatoid arthritis therapy.

Key words:
rheumatoid arthritis, liver, hepatitis B, drug-induced liver injury


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Dermatology & STDs Paediatric rheumatology Rheumatology
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