The Czech Rheumatological Society recommendations for monitoring the treatment safety in rheumatoid arthritis

Authors: L. Šedová 1;  J. Štolfa 1;  P. Horák 2;  K. Pavelka 1
Authors‘ workplace: Revmatologický ústav, Praha, 2III. interní klinika FN a LF UP Olomouc 1
Published in: Čes. Revmatol., 17, 2009, No. 1, p. 4-9.
Category: Original Papers


The report follows the Czech Rheumatological Society recommendations for the treatment of rheumatoid arthritis, which deal with the strategy and efficacy of treatment approaches. Herein, we deal with ways of monitoring the treatment safety with agents from the DMARDs group (disease modifying antirheumatic drugs), as well as nonsteroidal anti-inflammatory drugs. The report is divided according to particular agents. In DMARDs, their main toxicity is stated, in nonsteroidal anti-inflammatory drugs, the gastrointestinal, cardiovascular, renal and other toxicity is analysed with special notes to coxibs. The necessary tests prior to the start of treatment and regular periodic follow-ups during the treatment are listed. Notes to pregnancy, lactation and basic vaccinations are presented, as well. In the last part, the pre-operative preparation of patients with rheumatoid arthritis is mentioned.

Key words:
treatment safety in rheumatoid arthritis, toxicity of DMARDs, NSAIDs, pregnancy, lactation, pre-operative preparation


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Dermatology & STDs Paediatric rheumatology Rheumatology
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