Rheumatoid arthritis withoutdevelopment of erosive changes

Authors: J. Rovenský;  D. Mičeková;  Z. Kmečová 1;  M. Stančíková;  J. Gatterová 2;  J. Bakošová
Authors‘ workplace: Národný ústav reumatických chorôb, Piešťany 1Reumatologická ambulancia, Roosveltovej nemocnice, Banská Bystrica 2Revmatologický ústav, Praha
Published in: Čes. Revmatol., , 2004, No. 1, p. 36-38.


The authors describe course of highly active seropositive rheumatoid arthritis without developmentof bony erosions even after 14 years of disease duration. In spite of the absence of erosive changes,there is no doubt about the diagnosis of rheumatoid arthritis due to criteria being present (6 criteriaof Arnett et al., 1987). The development of such a form of rheumatoid arthritis with no erosions andits possible causes are discussed in this case report. The effect of the treatment with low doses ofglucocorticoids is discussed, which is in agreement with literature data. Possible role of geneticfactors and inflammatory mediators in the initiation of erosions is analysed.

Key words:
radiological progression, erosive changes of RA, glucocorticoid therapy of early RA,inflammatory mediators

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Dermatology & STDs Paediatric rheumatology Rheumatology
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