Early detection of nervous system dysfunctionin patients with systemic lupus erythematosus by evoked potentials – a case report
I. Štětkářová 1; M. Veselá 2; O. Kryštůfková 2
Neurologické oddělení Nemocnice Na Homolce, Praha2Neurologická ambulance, Revmatologický ústav, Praha
Čes. Revmatol., , 2003, No. 2, p. 99-103.
In patients with verified diagnosis of systemic lupus erythematosus (SLE)without any topical signsof central nervous system impairment, the visual, brainstem auditory, somatosensory, and motorevoked potentials were performed. Small hyperintensive lesions supra- and infratentorial in whitematter were detected by MRI.We found and abnormal median cortical response and absence and/orshortening of silent period after transcranial magnetic stimulationwhich we interpreted as a slightdysfunction of supraspinal and/or cortical somatosensory generator of inhibitory interneurons inthe motor cortex. Multimodal evoked potentials could become a useful electrophysiological methodto detect subclinical central nervous impairment in SLE.
vasculitis, systemic lupus erythematosus, evoked potentials, somatosensory evokedpotentials, motor evoked potentials, lupus cephalgia
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