Comparison of Expression of Apoptosis in SecretionEndometrium of Natural Menstrual Cycle

Authors: P. Havelka 1,3;  I. Oborná 2;  V. Lichnovský 3;  M. Kršková 4;  H. Fingerová 3;  J. Březinová 3
Authors‘ workplace: Gynekologicko-porodnické oddělení Baťovy nemocnice, Zlín, přednosta prim. MUDr. F. Zábranský, CSc. 2Gynekologicko-porodnická klinika, LF UP a FN, Olomouc, přednosta prof. MUDr. M. Kudela, CSc. 3Ústav histologie a embryologie, UP, Olomouc přednosta prof. M 1
Published in: Čes. Gynek.2004, , č. 1 s. 15-19


Comparison of level of apoptosis in the mid-secretory human endometrium.Design: Clinical-laboratory trial.Setting: Department of Gynecology and Obstetrics, Medical Faculty, Palacký University, FacultyHospital, Olomouc, Department of Gynecology and Obstetrics, Bata Hospital, Zlín.Methods: Samples of secretory endometrium were obtained from 14 women. The women includedin the study had the next criteria: a history of infertility of more than 12 months, regular menstrualcycles, age below 40 and FSH basal level range 5-9 IU/L. Sampling of tissue was performedafter confi rmed ovulation by LH surge and repeated ultrasound examinations. Patterns wereprocessed by routine methods and apoptosis was detected using TUNEL assay.Results: The level of apoptosis in the endometrial epithelial surface was signifi cantly higher onday +7 compared to day +5 after ovulation (P

Key words:
apoptosis, endometrium

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Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine

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2004 Issue 1

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