The Use of Intravitreal Ranibizumab Application in the Treatment of Post-inflammatory Neovascular Membranes – a Case Report


Authors: V. Matušková ;  D. Vysloužilová
Authors‘ workplace: Oční klinika FN Brno Bohunice, přednostka prof. MUDr. Eva Vlková, CSc.
Published in: Čes. a slov. Oftal., 66, 2010, No. 2, p. 89-91
Category: Case Report

Overview

The aim of this case report is to represent our experience with intravitreal application of ranibizumab in a patient with post-inflammatory neovascular membrane. Patient, a 46 years old male, complained about 3 months lasting metamorphopsia in the left eye. The classic post-inflammatory neovascular membrane was diagnosed by means of fluorescein angiography. The initial BCVA of the left eye was 4/6 (or 0.67). Two intravitreal injections of 0.5 mg ranibizumab each were applied. After two applications, the BCVA was 4/4 (or 1.0), there was no biomicroscopically detectable edema, and the OCT revealed reestablished foveolar depression. This condition remains stable even after 10 months after beginning of the treatment. The anti-VEGF treatment represents another possibility of the treatment of post-inflammatory neovascular membranes.

Key words:
post-inflammatory neovascular membrane, anti-VEGF treatment, ranibizumab, intravitreal application.


Sources

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2. Ferrara, N., Damico, L., Shamá, N. et al.: Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration. Retina, 26, 2006: 859–870.

3. Rosenfeld, P.J., Brown, D.M., Heier, J.S. et al.: Ranibizumab for neovascular age-related macular degeneration. N Engl J Med.,14, 2006 :1419–31.

4. Ruiz-Moreno, J.M., Montero, J.A., Arias, L. et al.: Photodynamic therapy in subfoveal and juxtafoveal idiopathic and postinflammatory choroidal neovascularization. Acta Ophthalmologica Scandinavica, 84, 2006:743–748.

5. Vysloužilová, D., Kolář. P., Polanská, V. : PDT v léčbě klasických neovaskulárních membrán – naše zkušenosti. Sborník abstrakt XVI. výročního sjezdu České oftalmologické společnosti, 2008, ISBN 978-80-87009-53-6.

Labels
Ophthalmology
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