The New Era of Endovascular Therapy in the Treatment of Acute Stroke


Authors: M. Tinková;  P. Malý
Authors‘ workplace: Komplexní cerebrovaskulární centrum, Neurologické oddělení, ÚVN – VFN Praha
Published in: Cesk Slov Neurol N 2016; 79/112(2): 152-159
Category: Review Article

Overview

The endovascular therapy (EVT) is the most efficacious treatment for recanalisation of large vessel artery occlusion. Recently published prospective randomized controlled trials (RCT) demonstrated better outcomes with combined EVT and intravenous thrombolysis (IVT) versus IVT alone in the treatment of proximal arterial occlusion in the anterior cerebral circulation. In this article seven of these RCT studies published in 2014 - 2015 are reviewed. In the latter part of the article, the factors influencing final clinical outcome are discussed: age, comorbidities, hyperglycemia on admission, signs of early ischemia as evaluaed by Alberta Stroke Program Early CT Score (ASPECTS), absence of collateral supply, time before recanalisation occurs and application general anesthesia. The careful selection of patients indicated for EVT is of utmost importance for the succes of therapy.

Key words:
acute ischemic stroke – endovascular therapy – mechanical thrombectomy – stent-retriever

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.


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