Biomarkers of Multiple Sclerosis –  Current Options and Future Perspectives


Authors: J. Piťha
Authors‘ workplace: Neurologické oddělení, Krajská zdravotní, a. s. – Nemocnice Teplice o. z.
Published in: Cesk Slov Neurol N 2015; 78/111(3): 269-273
Category: Review Article

Overview

Multiple sclerosis is a chronic disease of the central nervous system of unknown etiology with manifestations of autoimmune inflammation and neurodegeneration. The disease is heterogeneous with an unpredictable outcome. The course of the disease can be monitored with clinical parameters as well as pathological changes on magnetic resonance imaging. Even though the effects of newly introduced drugs are known from clinical trials, it is not possible to predict their efficacy in a specific patient. Therefore, efforts have intensified over the recent years to identify laboratory markers that would as reliably as possible answer questions on subclinical disease activity, its progression and would facilitate therapeutic decisions based personalized medicine.

Key words.
multiple sclerosis – therapy – biomarkers

The author declare he has no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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