Occurence of Peripheral Primitive Neuroectodermal Tumor within Spinal Nerve Root –  a Case Report


Authors: P. Buchvald 1;  P. Barsa 1;  A. Blüml 2;  R. Lukáš 3
Authors‘ workplace: Neurocentrum, Neurochirurgické oddělení, Krajská nemocnice Liberec, a. s. 1;  Oddělení patologie, Krajská nemocnice Liberec, a. s. 2;  Traumatologicko-ortopedické centrum, Krajská nemocnice Liberec, a. s. 3
Published in: Cesk Slov Neurol N 2015; 78/111(3): 344-347
Category: Case Report

Overview

Peripheral primitive neuroectodermal tumor (pPNET) is a highly malignant soft tissue sarcoma probably originating from embryonic neural crest cells. For some common cytological, immunohistochemical and cytogenetic features with bone Ewing’s sarcoma, pPNET is also sometimes inaccurately referred to as Ewing’s sarcoma of soft tissues. pPNET probably is a different morphological expression of the same tumor type. pPNET mainly occurs in younger patients in various locations, always in close proximity to a peripheral nerve. However, its occurrence within a spinal nerve root is very rare and, so far, only a few cases have been described in the literature. In our report, we present a case of 35-year-old woman with pPNET in extraforaminal projection of L5 root. As a result of early diagnosis and treatment, including radical surgery combined with aggressive chemotherapy and irradiation of the tumor bed, no recurrence has been reported so far. The follow-up period is more than five years.

Key words:
peripheral primitive neuroectodermal tumor – spinal nerve root – neurosurgery – chemotherapy – radiotherapy

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manu­script met the ICMJE “uniform requirements” for biomedical papers.


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Labels
Paediatric neurology Neurosurgery Neurology

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Czech and Slovak Neurology and Neurosurgery

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