Sulodexide in angiological patients

Authors: K. Roztočil
Authors‘ workplace: Klinika transplantační chirurgie, Institut klinické a experimentální medicíny, Praha
Published in: Kardiol Rev Int Med 2014, 16(4): 336-339
Category: Internal Medicine


Sulodexide is a compound belonging to the group of glycosaminoglycans (together with heparins). In comparison with other glycosaminoglycans, sulodexide has stronger antithrombotic properties and a lower risk of bleeding, and unlike heparin, it can be administered both parenterally and orally. Multiple pharmacodynamic effects of the preparation have been demonstrated. Clinical studies have documented the effectiveness of the drug in patients with claudication. There is evidence of its effect also in patients with the most severe cases of chronic venous insufficiency, including patients with active leg ulcers. In the case of a positive outcome of the ongoing studies, secondary prevention of venous thrombosis will be added as another indication.

sulodexid –  glykosaminoglykany –  claudication – leg ulcers – venous thrombosis


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