Risks of anaesthesia in children with Angelman syndrome
Authors:
Hladíková Andrea 1; Olos Tomáš 2; Hladík Michal 2; Šilhánová Eva 1
Authors‘ workplace:
Oddělení lékařské genetiky, FN Ostrava
1; Klinika dětského lékařství FN Ostrava a LF Ostravské univerzity
2
Published in:
Anest. intenziv. Med., 23, 2012, č. 4, s. 183-187
Category:
Anaesthesiology - Review articles
Overview
The authors would like to make you aware of the unpredictable effects of anaesthetic agents in children with Angelman syndrome (a rare neuro-genetic disorder characterized by intellectual and developmental disability, epilepsy, sleep disturbance, seizures, jerky movements – especially hand-flapping, frequent laughter or smiling, usually a happy demeanour, microcephaly, plagiocephaly, prominent mandible, wide mouth, wide-spaced teeth, hypopigmentation, tongue thrusting, suck/swallowing disorders). Especially vagal hypertonia resulting in cardiac rhythm disturbances and asystole should be considered in the peri-operative care of these patients. Their recovery may be unpredictable and complicated.
Keywords:
Angelman syndrome – anaesthetic risk – difficult airway – vagal hypertonia
Sources
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Labels
Anaesthesiology, Resuscitation and Inten Intensive Care MedicineArticle was published in
Anaesthesiology and Intensive Care Medicine
2012 Issue 4
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