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Alzheimer's Disease –⁠ Another Pandemic on the Horizon?

11. 2. 2022 Source: Cognitive in the treatment of Alzheimer's disease

Due to the COVID-19 pandemic, other current problems often get pushed into the background. One of these is the aging population and the increasing prevalence of dementia. The key question thus becomes how to extend the period of active aging as much as possible.

Current Treatment Options for Multiple Myeloma

Multiple myeloma (MM) accounts for about 10% of all hematologic malignancies. Thanks to advancements in diagnostic methods, it is now understood as a collection of several cytologically distinct…

10. 2. 2022 Source: Hematologic Malignancies

In decisions about therapeutic strategy in multiple myeloma, patient preferences and concerns also play a crucial role

The perspective on the preferences of patients with multiple myeloma (MM) is very necessary at a time of rapid development of new treatment options. Patient priorities and their perception of…

10. 2. 2022 Source: Hematologic Malignancies

Pharmacokinetic Comparison of Two EHL Products in Hemophilia A

According to a Canadian study published last year, certain pharmacokinetic differences were observed between two extended half-life factors.

8. 2. 2022 Source: Hemophilia

Efficacy and Safety of the Combination of Telmisartan and Amlodipine with Hydrochlorothiazide in the Treatment of Hypertension

The aim of the study by Korean authors was to evaluate the efficacy and tolerability of the triple combination of telmisartan/amlodipine + hydrochlorothiazide (TAH) compared to the combination of…

8. 2. 2022 Source: Sartans in the Treatment of Hypertension

nemocniční postel rozhovor lékaře s pacientem

Effect of Administering Ferric Carboxymaltose on Quality of Life in Heart Failure Patients

The quality of life in patients with heart failure is significantly reduced. The concurrent occurrence of iron deficiency further exacerbates this situation. The AFFIRM-AHF study evaluated the impact…

7. 2. 2022 Source: Iron Deficiency and Anemia

CASE STUDY: Surgical Procedure in an Adolescent Patient with Severe Hemophilia A on Emicizumab Prophylaxis

This case study is narrated by MUDr. Bohumír Blažek from the Clinic of Pediatric Medicine at LF OU and FN Ostrava. The patient is a 17-year-old boy with severe hemophilia A. Several months prior to the...

1. 2. 2022 Source: Quality Life Even with Hemophilia

Practical Two-Point Pharmacokinetic Protocol in Hemophilia A

A recently published study confirmed the practicality of a shortened and simple pharmacokinetic protocol for patients with hemophilia A.

31. 1. 2022 Source: Hemophilia

srdce strava jídlo životní styl diabetes kardiovaskulární

Diabetic Cardiovascular Autonomic Neuropathy: How to Detect This Serious Diagnosis and Why Is It Dangerous?

Diabetic autonomic neuropathy can affect various organ systems. Cardiovascular autonomic neuropathy is one of its most severe forms with a significant impact on patient morbidity and mortality. How…

27. 1. 2022 Source: Diabetes

Memantine in Dementia Therapy –⁠ Current Findings and Possible Future Applications

Memantine is an inhibitor of NMDA receptors, which are pathologically activated by excessive concentrations of glutamate in the synaptic cleft in Alzheimer's disease. It is indicated in the treatment…

26. 1. 2022 Source: Cognitive in the treatment of Alzheimer's disease

Dupilumab Now Covered for Atopic Dermatitis in Children Older Than 6 Years

Dupilumab is now fully covered by public health insurance for pediatric patients from 6 years old with atopic dermatitis. This opens up a new possibility for pediatric patients with this condition to…

22. 1. 2022 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Recurring allergy symptoms after waking up? It could be due to dust mites

Allergens that are part of the feces and exoskeleton of dust mites, invisible members of human households, can cause milder symptoms like mucosal swelling, itching of the nose or throat, but also a stronger...

19. 1. 2022 Source: Dust Mite Allergy

Reverse Remodeling of LV in Patients with Diabetes/Prediabetes and Heart Failure with Reduced Ejection Fraction Treated with Empagliflozin

Authors of the British study SUGAR-DM-HF published in February 2021 examined whether empagliflozin reduces left ventricle (LV) volume in patients with type 2 diabetes mellitus (DM), prediabetes, and…

14. 1. 2022 Source: Heart Failure

Current Status in the Issue of Alpha-1-Antitrypsin Deficiency

Material by Italian and Swiss authors published in the European Respiratory Review details current insights into alpha-1-antitrypsin (AAT) deficiency and the possibilities for its diagnosis and…

12. 1. 2022 Source: Deficiency of Alpha-1-Antitrypsin

Mental Health During the Pandemic −⁠ and How to Alleviate Its Impacts

At the symposium during the XV Spring Interactive Conference of the General Medical Society of ČLS JEP, which was eventually held in September 2021 in Prague, Prof. MUDr. Cyril Höschl, DrSc.,…

10. 1. 2022 Source: Depression and Anxiety

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