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Maintaining Therapeutic Doses of Levothyroxine Throughout Shelf Life

23. 2. 2022 Source: Thyroid Disorders

Levothyroxine is the drug of choice for patients with hypothyroidism. However, it is also one of the substances with a narrow therapeutic range, which increases the risk of overdose or underdose, especially in risk groups. An innovative formulation of levothyroxine guarantees the maintenance of the drug content within the range of 95–105% throughout the shelf life of the product.

štítná žláza  lékař na pozadí

Is there a link between Parvovirus B19 infection and autoimmune thyroid diseases?

Autoimmune thyroid diseases are among the most common autoimmune disorders, with a worldwide prevalence of around 10%. The study presented below, recently published in the International Journal of…
23. 2. 2022 Source: Thyroid Disorders
dítě kapačky nemocnice

Safety of Dabigatran in Secondary Prevention of Venous Thromboembolism in Pediatric Patients

Low molecular weight heparin (LMWH) or warfarin (VKA –⁠ vitamin K antagonist) is typically used for the secondary prevention of venous thromboembolism. The DIVERSITY study extension examined the…
23. 2. 2022 Source: Anticoagulant Treatment
starší muž infarkt

How to Dose Beta-Blockers After Myocardial Infarction?

In patients after myocardial infarction (MI), there is a frequent administration of too low doses of beta-blockers (BB) and rare upward titration of their dose after discharge from the hospital. The…
23. 2. 2022 Source: Cardiovascular Continuum
tablety

How do patients perceive the change in appearance of chronically used medications and to what extent does it lead to non-adherence to therapy?

Doctors regularly encounter patients in their offices who complain about changes in the appearance of their chronically used medications. Such a change can even be the cause of non-adherence to…
23. 2. 2022 Source: Cardiovascular Continuum
bercove vredy

Analysis of the Benefits and Risks of Superabsorbent Dressings in the Treatment of Moderate to Highly Exuding Leg Ulcers

A study on the benefits and risks of superabsorbent dressings compared to standard dressings in the treatment of moderate to highly exuding leg ulcers was published last year in The International…
22. 2. 2022 Source: Wound Healing
model srdce ordinace

Proposal of a New Treatment Sequence Algorithm for Heart Failure with Reduced Ejection Fraction

John McMurray and Milton Packer published a proposal for a new treatment sequence algorithm for patients with heart failure with reduced ejection fraction (HFrEF) based on current findings in the…
21. 2. 2022 Source: Heart Failure
kongresový sál řečník

Fresh from ASH 2021: Promising results of the combination of azacitidine with venetoclax and magrolimab in the treatment of AML

Dr. Naval Daver and his colleagues from the Anderson Cancer Center in Houston presented an oral report during the December congress of the American Society of Hematology (ASH 2021) about a phase…
17. 2. 2022 Source: Chronic Lymphocytic Leukemia
komplikace diabetu

How Diabetes Shortens Life or Mortality of Patients with Type 2 Diabetes

Type 2 diabetes mellitus (DM) has a significant impact on overall mortality across age categories. Who is most affected by this disease in terms of age and gender, and what are the current trends in…
17. 2. 2022 Source: Diabetes
generika_pilikly_krabička_léky

Less is Sometimes More –⁠ How Generic Substitution Can Affect Patient Adherence

It is undisputed that the use of generic drugs saves the healthcare system significant costs. Although doctors should certainly care about the health of the system, they primarily care for the health…
17. 2. 2022 Source: Modern Treatment of Diabetes
měření cukrovky

Limits of Glycated Hemoglobin and the Importance of Other Glycated Proteins

Glycated hemoglobin is a gold standard in the diagnosis and management of diabetes treatment. However, its disadvantages include numerous factors that can cause false increases or decreases in its…
17. 2. 2022 Source: Modern Treatment of Diabetes
žena_kašel

Treatment of Cough in Clinical Practice: Which Preparations Are Suitable and When?

In clinical practice, we differentiate the treatment of non-productive and moist productive cough. When choosing appropriate therapy, we consider the characteristics of the available medicinal…
15. 2. 2022 Source: Cough Therapy
Dítě_kašel

Quo vadis, erdostein? Or the current and future potential of erdosteine in practice

Erdosteine has a well-established place in the therapy of acute respiratory diseases in children. Its mucolytic and antibacterial properties are very well documented. Recently, research has focused…
15. 2. 2022 Source: Cough Therapy
dítě_plíce

What is the effectiveness of levodropropizine in the treatment of children's cough?

Levodropropizine represents an effective and safe option for the treatment of acute irritating cough in children. How does it compare to dropropizine and commonly used centrally acting antitussives?
15. 2. 2022 Source: Cough Therapy
Endometriosis

Effects of Progestins in Combination with EE on Endothelial Function, Lipid Levels, and Oxidative Stress in Women with Endometriosis

Studies have shown endothelial dysfunction and increased oxidative stress in women with endometriosis. Theoretically, they may be at increased cardiovascular risk. The study presented below…
15. 2. 2022 Source: Oral Contraception
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