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konzultace lékařka a seniorka

Adequate Anti-Xa Levels Are More Often Achieved in Trauma Patients When Dosing Enoxaparin Based on Weight

3. 3. 2022 Source: Thromboprophylaxis

Thromboembolic disease (TED) is a well-known preventable cause of morbidity and mortality in trauma patients. To improve their prognosis, pharmacological thromboprophylaxis, such as with low molecular weight heparins (LMWH), is an essential part of treatment. However, previously published studies have pointed out that standard dosing of LMWH may be associated with insufficient levels of activity measured using the anti-Xa parameter.

modřina kotník

Is Dupilumab Effective in AD Therapy for Patients for Whom Cyclosporine A Fails or Cannot Be Given?

Severe forms of atopic dermatitis (AD) may require systemic therapy. However, the immunosuppressant cyclosporine A does not have sufficient efficacy in some patients with AD or is contraindicated for…
3. 3. 2022 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation
operace chirurgové

Use of Specific Inhibition of Anticoagulant Therapy During Heart Transplantation

A recent report from real clinical practice summarizes the experiences of physicians with dabigatran therapy and the reversal of its anticoagulant effect using idarucizumab in 10 patients before…
1. 3. 2022 Source: Anticoagulant Treatment
žíla_krev

Micronized Diosmin Obtained Reimbursement, Based on Its Therapeutic Interchangeability with MPFF

On January 11, 2022, the State Institute for Drug Control (SÚKL) issued a decision on the determination of the amount and conditions of reimbursement from health insurance for a drug containing…
28. 2. 2022 Source: Venous Insufficiency
molekula metamizol

Metamizole, even after 100 years on the market, remains an important component of postoperative pain therapy

Metamizole has been used in the therapy of a wide range of acute and chronic pains for 100 years. Thanks to a number of advantages, it still represents one of the most frequently used analgesics in…
28. 2. 2022 Source: Analgesia
plíce_kašel

Administration of Erdosteine after Severe COVID-19 in the Early Period after Discharging Patients from the Healthcare Facility

Erdosteine is a mucomodulatory drug used in the treatment of various acute and chronic respiratory diseases. According to available evidence, its mechanism of action is complex, encompassing not only…
28. 2. 2022 Source: Cough Therapy
nemocniční postel rozhovor lékaře s pacientem

Even in Severe Cases of HAE, Individualized Treatment is Crucial –⁠ Case Study

As part of the case seminar from the HAExpert series, held on December 1, 2021, which specifically focused on the treatment of hereditary angioedema (HAE) in specific patients, Dr. Roman Hakl from…
25. 2. 2022 Source: Hereditary Angioedema
otok

Orally Administered Berotralstat in the Prevention of Hereditary Angioedema Attacks

Berotralstat is an oral medication administered once daily, developed to prevent hereditary angioedema (HAE) attacks. It is a kallikrein protease inhibitor, which plays a key role in the pathogenesis…
25. 2. 2022 Source: Hereditary Angioedema
diagnoza

Current (and Future) Possibilities for Diagnosing Alpha-1-Antitrypsin Deficiency

Alpha-1-antitrypsin deficiency (AAT) is associated, among other things, with the development of chronic obstructive pulmonary disease (COPD) with emphysema. Most patients, however, remain undiagnosed…
25. 2. 2022 Source: Deficiency of Alpha-1-Antitrypsin
notebook studie výzkum medicína

How and What the National AATD Register Benefits Experts and Patients

Given that alpha-1-antitrypsin deficiency (AATD) is still not receiving enough attention, it is necessary to raise professional awareness of this hereditary disease by all means. This is also one of…
25. 2. 2022 Source: Deficiency of Alpha-1-Antitrypsin
Konference_přednáška_vzdělávání_edukace_lékaři

How and How the Czech National Hemophilia Program Benefits Professionals and Patients

The Czech National Hemophilia Program (ČNHP) has been an interdisciplinary initiative for many years, coordinating specialized care for both pediatric and adult patients with hemophilia and other…
25. 2. 2022 Source: Von Willebrand Disease
roztok rany

Analgesic Effects of Using Ringer's Solution in Wound Healing Management

Pain resulting from skin defects of various etiologies causes significant discomfort for the patient. However, wound care using Ringer's solution and the use of primary dressings, which include this…
25. 2. 2022 Source: Wound Healing
hojeni ran roztok

Wound Treatment Without Pain? A Rinse Solution Can Help

Patients dealing with a healing wound may fear painful dressing changes. The wound bed is exposed and highly sensitive to pain due to damaged nerve endings. By using a rinse solution, however, we can…
25. 2. 2022 Source: Wound Healing
srdeční selhání 4

How to recognize amyloidosis as a cause of heart failure?

Although the fate of patients with heart failure has improved in recent decades, it remains a disease with a poor prognosis that significantly worsens the quality of life. The prevalence of heart…
24. 2. 2022 Source: Amyloidosis
chripka a nachlazení

Inosine pranobex in the treatment of influenza and other respiratory infections of viral etiology

The antiviral inosine pranobex is a clinically proven immunomodulator for the treatment of patients from 1 year of age, indicated for a wide range of diseases with manifestations of immune…
24. 2. 2022 Source: Viral infections
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