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Impact of Tofacitinib on the Quality of Life of Patients with Ulcerative Colitis

7. 12. 2023 Source: Intestinal Inflammations

Tofacitinib is an oral Janus kinase (JAK) inhibitor used in the treatment of certain rheumatic diseases and ulcerative colitis (UC). The work presented at this year's 18th congress of the European Crohn's and Colitis Organization (ECCO) in Copenhagen, Denmark, focused on its impact on the quality of life in terms of physical and mental functions in patients with UC.

Use of Testosterone Level as a Biomarker for Quality of Life in Patients with Prostate Cancer

In the treatment of prostate cancer, in addition to surgical treatment, stereotactic body radiotherapy (SBRT) and hormone therapy are also used. Androgen deprivation therapy (ADT) blocks the action…

6. 12. 2023 Source: Oncological Treatment

How Does Empagliflozin Stand in Terms of Diabetic Retinopathy Risk? We Have Answers Not Only from Controlled Studies but Also from Real Practice

Modern antidiabetics –⁠ gliflozins and glucagon-like peptide-1 receptor agonists (GLP-1RA) –⁠ significantly help improve the management of type 2 diabetes (DM2). In addition to reliable glycemic…

5. 12. 2023 Source: Diabetes

The Significance of Administering Gliflozins in Real Practice in Diabetics Without CV and Renal Disease

Current care standards recommend the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i, i.e., gliflozins) regardless of glycemic compensation in patients with type 2 diabetes (T2DM) and kidney…

5. 12. 2023 Source: Diabetes

Doc. Miloslav Salavec: We Still Encounter Delayed Initiation of Biological Treatment in AD and Many Other Diagnoses

Not all patients with atopic dermatitis (AD) who are indicated for biological treatment with dupilumab manage to reach centers where the treatment is provided. It's even more unfortunate when there's…

4. 12. 2023 Source: Systemic treatment of atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis – Type 2 inflammation

Dual Inhibition of IL-17A/IL-17F Across the Spectrum of Axial Spondyloarthritis

Many patients with axial spondyloarthritis (axSpA) still have a need to seek additional therapeutic options and new mechanisms of action for medicinal substances. Phase III studies BE MOBILE 1 and 2…

1. 12. 2023 Source: Rheumatic Diseases

Effectiveness and Safety of Initiating Treatment for Primary Immunodeficiency with Subcutaneously Administered Immunoglobulins –⁠ A Systematic Review of the Literature

The aim of the systematic review of the literature published last year was to evaluate the effectiveness and safety of initiating treatment with subcutaneously administered immunoglobulins (SCIG) in…

1. 12. 2023 Source: Primary and Secondary Immunodeficiencies

10 Warning Signs of Primary and Secondary Immunodeficiencies

The Jeffrey Modell Foundation (JMF) proposed 10 warning signs of primary immunodeficiencies (PID). The study presented below examined whether they are applicable to secondary immunodeficiencies (SID)…

1. 12. 2023 Source: Primary and Secondary Immunodeficiencies

Picking from the Red Book of the CHS: What's New in This Year's Recommendations for Diagnosis and Treatment of AML?

In recent years, there have been significant advances in the diagnosis and therapy of acute myeloid leukemia (AML). High-quality laboratory diagnostics (molecular genetics, cytogenetics, and flow…

29. 11. 2023 Source: Acute Myeloid Leukemia

Educational Brochure for Patients with CLL

Thanks to the expansion of modern therapies for chronic lymphocytic leukemia, many patients now have regimens based on venetoclax. Do you want to help them better understand the practical aspects and...

28. 11. 2023 Source: Chronic Lymphocytic Leukemia

Bacterial Biofilm as a Complication of Respiratory Disease Treatment

One of the unique characteristics of certain microorganisms is their ability to form organized communities enveloped in extracellular polymeric matrix and firmly attached to a solid surface or…

28. 11. 2023 Source: Cough Therapy

Impact of erdostein on bacterial biofilm −⁠ and what it means for clinical practice?

One of the substances that could potentially influence the success of treatments for infections associated with biofilm formation in the future is erdostein. This medication is used in the treatment…

28. 11. 2023 Source: Cough Therapy

Low Molecular Weight Heparin in an ECMO Patient −⁠ Case Study

Extracorporeal membrane oxygenation (ECMO) has an irreplaceable role in intensive care medicine. In the context of preventing complications caused by blood clot formation, unfractionated heparin is…

28. 11. 2023 Source: Thromboprophylaxis

Use of Enoxaparin in Patients After Implantation of Left Ventricular Assist Device

Left ventricular assist devices (LVAD) are utilized in patients with end-stage heart failure (HF). Warfarin is typically employed for long-term anticoagulation, but there are no standardized…

28. 11. 2023 Source: Thromboprophylaxis

Prophylaxis with Enoxaparin After Total Knee or Hip Replacement

Venous thromboembolic disease is a significant cause of complications in surgical patients during and after hospitalization. The authors of a recently published Portuguese observational study…

28. 11. 2023 Source: Thromboprophylaxis

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