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Generic Substitution of Levothyroxine in Practice
22. 2. 2024 Source: Thyroid DisordersThe active ingredient levothyroxine is found in a significant number of medicinal products (MP) in the Czech Republic. The question of its generic substitution remains current, primarily because the previously published data tend to call for caution due to possible adverse effects on the patient.
Options for Systemic Therapy of Advanced Stage Small Cell Lung Cancer
Small cell lung cancer (SCLC) is the most aggressive type of lung tumor. Although it responds well to chemotherapy and radiotherapy, due to the early onset of treatment resistance, the 5-year…22. 2. 2024 Source: Small Cell Lung Cancer
Current Sequence of Treatment for Metastatic HER2+ Breast Cancer
In September 2023, experts from Miami Cancer Institute published their consensus statement on the treatment of HER2-positive advanced breast cancer (BC). The latest change in therapeutic strategy is…22. 2. 2024 Source: Ovarian and Breast Cancer
Artificial Intelligence and Deep Learning as the Future of Glaucoma Diagnosis
Glaucoma represents a group of eye diseases characterized by changes to the optic nerve. It is the second most common cause of blindness, currently affecting more than 90 million people worldwide. It…21. 2. 2024 Source: proLékaře.cz
MUDr. Jana Zárubová: Experiences with buccal midazolam in real practice are positive and we can significantly improve patients' quality of life
Recently, it has emerged as an alternative to traditionally rectally administered diazepam for stopping prolonged convulsive seizures in patients with epilepsy. What can buccal midazolam offer them…21. 2. 2024 Source: Quick aid for acute convulsive seizures in children and adolescents
IEC 2023: Key Challenges for Epilepsy Patients Include Status Epilepticus and Anxiety Management
Why is anxiety a significant issue for epilepsy patients? What do current insights say about the connection between epilepsy and anxiety? Can artificial intelligence be used to predict status…21. 2. 2024 Source: Quick aid for acute convulsive seizures in children and adolescents
Ocrelizumab in the Treatment of Multiple Sclerosis – 10-Year Data
Multiple sclerosis (MS) is a lifelong disease with a high risk of permanent disability. Current information on the long-term efficacy and safety of treatment is therefore absolutely essential for the…20. 2. 2024 Source: Neurology - Multiple Sclerosis
Long-term Efficacy and Safety of Mavacamten in the Treatment of Obstructive HCM
Interim results of the MAVA-LTE study provide the latest data on the long-term safety and efficacy of symptomatic treatment with mavacamten for obstructive hypertrophic cardiomyopathy (oHCM), with…19. 2. 2024 Source: Hypertrophic Cardiomyopathy (HCM)
Mavacamten in the Treatment of HCM in Patients Referred for Septal Reduction
Extended 56-week follow-up of patients with hypertrophic cardiomyopathy (HCM) resistant to current pharmacotherapy in the VALOR-HCM study confirmed the lasting benefit of mavacamten – the first…19. 2. 2024 Source: Hypertrophic Cardiomyopathy (HCM)
How Does Myelodysplastic Syndrome Affect Patients' Quality of Life?
Myelodysplastic syndrome (MDS) is a heterogeneous group of disorders of hematopoietic stem cells with varying degrees of risk of progression to acute myeloid leukemia (AML). The therapeutic options…15. 2. 2024 Source: Myelodysplastic Syndrome (MDS)
Planning Surgery Using 3D Printing in Practice – Case Study
In October 2023, an article by neurosurgeons from Leipzig University was published in the journal 3D Printing in Medicine, focusing on the use of 3D printing in the treatment of complex…25. 1. 2024 Source: proLékaře.cz
Immunomodulation and Romiplostim − What Does the Recently Published iROM Study Say?
Primary immune thrombocytopenia (ITP) is caused by an immunity disorder, involving not only the production of antibodies but also changes in cytokine levels, predominance of Th1 lymphocytes over Th2,…24. 1. 2024 Source: Immune Thrombocytopenia
ICIS Report: Potential of TPO-RA as Early Immunomodulatory Treatment of Immune Thrombocytopenia
The report from the meeting of the Intercontinental Cooperative ITP Study Group (ICIS) in 2022 in Lenzerheide, Switzerland, published late last year in the British Journal of Haematology, discusses…24. 1. 2024 Source: Immune Thrombocytopenia
Impact of Azacitidine Maintenance Therapy on Survival of Patients with AML in Remission Depending on Initial Chemotherapy
The QUAZAR AML-001 study showed that oral azacitidine maintenance therapy significantly prolongs relapse-free survival (RFS) and overall survival (OS) in patients with acute myeloid leukemia (AML) in…24. 1. 2024 Source: Acute Myeloid Leukemia
Doc. Milan Sova: AAT substitution is available to all indicated patients. It is therefore crucial to now educate about the necessity of regular treatment
Alpha-1-antitrypsin deficiency (AATD) is one of the most common genetic disorders in adults. It is usually associated with the early development of chronic obstructive pulmonary disease (COPD) or…18. 1. 2024 Source: Deficiency of Alpha-1-AntitrypsinLogin#ADS_BOTTOM_SCRIPTS#Forgotten passwordEnter the email address that you registered with. We will send you instructions on how to set a new password.
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