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Medical News

roztroušená skleroza 22

Ocrelizumab in the treatment of multiple sclerosis in real-world practice –⁠ a systematic review of published studies

27. 9. 2023 Source: Neurology - Multiple Sclerosis

In controlled study programs, ocrelizumab has demonstrated beneficial effects on improving clinical parameters in patients with multiple sclerosis, such as the annual relapse rate or confirmed disability progression. However, to get a complete picture of its clinical benefit, real-world evidence in a broad patient population is also needed. A systematic review of real-world clinical practice studies with ocrelizumab, published in March 2023, demonstrates its benefits in patients with relapsing-remitting multiple sclerosis (RRMS) and primary…

krytí Zetuvit Plus Silicone Border

Innovation in Wound Healing: Zetuvit Plus Silicone Border for Optimal Wound Exudate Management

Excessive wound exudate can lead to delayed healing, skin damage around the wound, or leakage under the chosen dressing. Zetuvit Plus Silicone Border dressing with high absorbent and retention…
26. 9. 2023 Source: Wound Healing
ulcerative colitis

Current Data of Tofacitinib in the Treatment of IBD: What Improvements in Endoscopic and Histologic Outcomes Can Be Achieved?

The oral Janus kinase inhibitor (JAKi) tofacitinib is currently approved for the treatment of moderately to severely active ulcerative colitis (UC). Its efficacy and safety in this indication have…
20. 9. 2023 Source: Intestinal Inflammations
congres

Current News from ECCO 2023: Tofacitinib in the Treatment of Ulcerative Colitis in Real-World Practice

At the 18th ECCO Congress, held in March 2023 in Copenhagen, results from a Spanish real-world study were presented. This study evaluated the efficacy and safety of tofacitinib in the treatment of…
20. 9. 2023 Source: Intestinal Inflammations
karcinom nosohltanu

Proton radiotherapy in patients with nasopharyngeal carcinoma increases chances of successful treatment

Nasopharyngeal carcinoma mainly affects younger people. It tends to be aggressive but responds very well to treatment –⁠ up to 85% of patients with this diagnosis can achieve long-term tumor…
20. 9. 2023 Source: Proton Radiotherapy
roztroušená skleróza

Early Implementation of Highly Effective Therapy for Multiple Sclerosis

The ongoing debate about changing the approach to treating relapsing-remitting multiple sclerosis (RRMS) from an escalation strategy to the early implementation of highly effective therapy (HET) is…
20. 9. 2023 Source: Neurology - Multiple Sclerosis
mozek

Treatment Options for Advanced Parkinson's Disease Using Medical Devices (DAT)

A new treatment option for advanced Parkinson's disease (PD) using medical devices (DAT −⁠ device-aided therapy) is the intestinal infusion gel containing levodopa, entacapone, and carbidopa (LECIG).…
14. 9. 2023 Source: Parkinson's Disease
rucepomoc

Identification of patients with advanced Parkinson's disease suitable for device-aided therapy (DAT)

To properly implement device-aided therapy in Parkinson's disease (PD) management, it is essential to timely identify patients in advanced stages of the disease who might benefit from this…
14. 9. 2023 Source: Parkinson's Disease
léčba epilepsie

Do real-world clinical practice data confirm the results of cenobamate treatment in the clinical program?

A recent study by Spanish authors presents the largest dataset of patients with published cenobamate treatment results under prolonged observation in real-world clinical practice at the time of…
13. 9. 2023 Source: Epilepsy
Lékař_CT hlava

Cenobamate in the Therapy of Pharmacoresistant Epilepsy in a Warfarinized Patient –⁠ A Case Study

A case study from Czech practice presents a patient with pharmacoresistant epilepsy and concurrent warfarin medication for heart valve replacement, where the INR value remained within the…
13. 9. 2023 Source: Epilepsy
Gestační diabetes

Meta-analysis of Efficacy and Safety of Antidiabetics in Treating Gestational DM

What efficacy and safety do insulin, metformin, or the sulfonylurea derivative glibenclamide (glyburide) offer in lowering glucose levels in women with gestational diabetes? The authors of a…
13. 9. 2023 Source: Modern Treatment of Diabetes
oftamolog

How to Determine the Optimal Target Value of Intraocular Pressure in Glaucoma Treatment?

Glaucoma remains the second most common cause of blindness in Europe. Therapy needs to be individualized with regard to the severity of the condition, expected lifespan, and the rate of disease…
8. 9. 2023 Source: Treatment of Glaucoma
kardiomyopatie

Hypertrophic Cardiomyopathy: When Bigger Does Not Mean Better

Hypertrophic cardiomyopathy (HCM) is a hereditary disease that, in some patients, proceeds asymptomatically, while others struggle with arrhythmias or heart failure, and in some individuals, the…
7. 9. 2023 Source: Hypertrophic Cardiomyopathy (HCM)
lidské srdce

Why does the heart enlarge? Myosin mutation and hypertrophic cardiomyopathy may be the culprits

The genetic basis of hypertrophic cardiomyopathy was discovered only about a quarter-century ago. Since then, researchers have gathered a wealth of knowledge about the effects of causal mutations.…
7. 9. 2023 Source: Hypertrophic Cardiomyopathy (HCM)
doc. Ludmila Brunerová

Current View on Gestational Diabetes Mellitus in Theory and Practice

We dedicated one of the episodes of our podcast meditalks+ to the issue of gestational diabetes mellitus (GDM), focusing on aspects of care related to general practitioners. In a conversation with …
7. 9. 2023 Source: Modern Treatment of Diabetes
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