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Long-term treatment of ozanimod in patients with moderate to severe ulcerative colitis

21. 8. 2023 Source: Modulation of S1P in the Treatment of Autoimmune Diseases

The immunosuppressive ozanimod was approved for the treatment of ulcerative colitis (UC) based on the results of the phase III clinical trial True North. An open-label study followed this and previous clinical evaluations, focusing particularly on the efficacy of long-term use of ozanimod. What insights did the subsequent monitoring bring?

Can SGLT2 Inhibition Also Reduce the Risk of Nephrolithiasis?

Diabetes mellitus (DM) is a risk factor for the development of nephrolithiasis. Recent studies associated with nephrolithiasis suggest a possible beneficial effect of sodium-glucose cotransporter 2…

21. 8. 2023 Source: Diabetes

MS in the Digital Age: Doctor as a Lifebuoy in the Sea of Information

How to offer a helping hand to patients amidst the flood of information and why is communication perhaps more important than ever? And what should the standards in the doctor-patient relationship…

15. 8. 2023 Source: Multiple Sclerosis

Can Antihypertensives Reduce the Risk of Dementia? The Answer Suggests the Angiotensin Hypothesis and a Post-Hoc Analysis of an Observational Study

The use of antihypertensives that do not reduce angiotensin II levels, such as angiotensin receptor blockers (ARBs, i.e., sartans) and calcium channel blockers (CCBs), has been associated with a…

14. 8. 2023 Source: Sartans in the Treatment of Hypertension

What Results Does Bimekizumab Achieve in Patients with PsA After 3 Years of Treatment?

Fresh findings from the BE ACTIVE study were published this year in the journal Rheumatology, which evaluated the effects of long-term treatment of individuals with psoriatic arthritis (PsA) with…

10. 8. 2023 Source: Psoriasis

Can Empagliflozin Also Act Against Gout?

Gliflozins, or sodium-glucose cotransporter 2 inhibitors (SGLT2i), are not only effective antidiabetic agents but also exhibit cardio -⁠ and renoprotective effects. It now appears that in type 2…

21. 7. 2023 Source: Diabetes

How does the level of uric acid affect the incidence of cardiorenal events in patients with T2DM and CVD?

One of the post hoc analyses of the well-known EMPA-REG OUTCOME study provided data on the relationship between uric acid levels and the incidence of cardiorenal events in type 2 diabetics with…

21. 7. 2023 Source: Diabetes

Currently on the Issue of Interchangeability of Preparations with Levothyroxine in Practice

Levothyroxine (LT4) in oral form is the standard therapy for patients with hypothyroidism. Given the legislative possibility of generic substitution and the number of original and generic preparations...

17. 7. 2023 Source: Thyroid Disorders

INFOGRAPHIC: Determining the Target Intraocular Pressure in Glaucoma Therapy

The goal of glaucoma treatment is to preserve the visual field and the quality of life of patients. Currently, the only approach to preserving the visual field of patients is to reduce intraocular…

14. 7. 2023 Source: Treatment of Glaucoma

Effectiveness of Bisoprolol in Patients with Cardiac Arrhythmias –⁠ A Systematic Review of Studies

Last year, a Franco-Romanian team published a study that conducted a systematic review of existing evidence on bisoprolol in the context of arrhythmia treatment. The authors noted that bisoprolol,…

12. 7. 2023 Source: Cardiovascular Continuum

Which biomarkers can be used for risk stratification in ATTR cardiac amyloidosis?

Effective treatment for patients with transthyretin cardiac amyloidosis requires timely diagnosis and precise risk stratification to identify patients at higher risk of cardiovascular events, heart…

11. 7. 2023 Source: Amyloidosis

Results of a 10-year follow-up on the safety and efficacy of etanercept treatment in patients with juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA) is defined as persistent arthritis of unknown etiology lasting > 6 weeks with the first onset before the age of 16. In the treatment of JIA, non-steroidal…

10. 7. 2023 Source: Arthritis

Tofacitinib Through the Eyes of Patients: Rapid Response After Treatment Initiation

How does tofacitinib fare in the treatment of ulcerative colitis in real clinical practice from the patients' perspective? This was addressed in a recent study published in the journal Inflammatory…

5. 7. 2023 Source: Intestinal Inflammations

Mental Health as an Overlooked Topic in Patients with Psoriasis

Psoriasis is an inflammatory, non-infectious disease primarily affecting the skin, and sometimes the nails, although in some patients, it manifests as psoriatic arthritis. To minimize the negative…

4. 7. 2023 Source: Psoriasis

Current Expert Consensus on Prophylaxis of Individuals with Mild and Moderate Hemophilia A: These Patients Also Deserve Better Care

What is the importance of prophylaxis in 'non-severe' hemophilia A? Italian doctors have attempted to answer this question in their recent expert consensus.

4. 7. 2023 Source: Hemophilia

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