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Medical News

anemia

Treatment of Low-Risk MDS According to NCCN Recommendations Version 1.2023

20. 10. 2023 Source: proLékaře.cz

The latest recommendations from the American National Comprehensive Cancer Network (NCCN) for the diagnosis and treatment of myelodysplastic syndrome (MDS) include several updates incorporated into the graphical algorithms. Most patients with MDS have low-risk (LR) disease. We provide a summary of the current guidelines NCCN for the therapy of this group of patients, which differ depending on the presence of symptomatic anemia or clinically relevant thrombocytopenia or neutropenia.

Covid19

ERS 2023: Erdostein and its Metabolite Met-1 Modulate Innate Immunity and Oxidative Stress in SARS-CoV-2 Infection

As part of the September congress of the European Respiratory Society (ERS 2023), the issue of COVID-19 was also addressed. Among the late-breaking messages was an e-poster by experts from the…
18. 10. 2023 Source: Cough Therapy
ledviny

Benefit of Empagliflozin in Patients with Chronic Kidney Disease –⁠ Results of the EMPA-KIDNEY Study

The sodium-glucose cotransporter 2 inhibitor (SGLT2i) empagliflozin is currently used to treat type 2 diabetes mellitus (T2DM) and chronic heart failure regardless of ejection fraction value. Its…
18. 10. 2023 Source: Diabetes
srdce

Cardio-Renal-Metabolic Syndrome?

The association between type 2 diabetes (DM2) and atherosclerotic cardiovascular disease (ASCVD) is often referred to as cardiometabolic syndrome, while the relationship between chronic kidney…
18. 10. 2023 Source: Diabetes
kongres

The Latest Updates of ESC Recommendations for Heart Failure Treatment

What is new in heart failure therapy? At the annual congress of the European Society of Cardiology (ESC), held from August 25–28, 2023 in Amsterdam, updates to clinical guidelines were traditionally…
18. 10. 2023 Source: Heart Failure
rectal cancer

Experience with Proton Radiotherapy for Anal Canal Carcinoma in Real Czech Practice

Radiotherapy has the potential to achieve complete tumor regression in patients with anal carcinoma, representing an effective alternative to radical surgery. However, it is associated with…
16. 10. 2023 Source: Proton Radiotherapy
data_medicine

Facilitated Immunoglobulin Substitution Therapy in Paediatric Patients with Immunodeficiency –⁠ Real-World Data

Patients with humoral immunodeficiency are indicated for immunoglobulin substitution therapy. The study presented below summarizes real-world data concerning the latest substitution method (i.e.,…
16. 10. 2023 Source: Primary and Secondary Immunodeficiencies
nemocnice

Incidence of Osteoporosis in Patients with Atrial Fibrillation Treated with Different Oral Anticoagulants

Previous research has suggested an increased risk of osteoporosis and osteoporotic fractures in patients with atrial fibrillation treated with warfarin. A recent analysis also identified a higher…
16. 10. 2023 Source: Anticoagulant Treatment
maternity

Results of Levothyroxine Treatment in Pregnant Women with Recurrent Pregnancy Losses with Subclinical Hypothyroidism or Anti-TPO Antibody Positivity

A recent meta-analysis of 15 studies involving a total of 1911 women with a history of recurrent pregnancy losses and positivity for thyroid peroxidase antibodies (TPOAb) or subclinical…
16. 10. 2023 Source: Thyroid Disorders
codid pacient

Nirmatrelvir/ritonavir reduces the risk of hospitalization for COVID-19 even in the era of predominant omicron subvariants BA.4 and BA.5

One of the first studies to evaluate the efficacy of nirmatrelvir/ritonavir in non-hospitalized patients with COVID-19 infection during the period of predominant omicron variants including…
16. 10. 2023 Source: COVID-19
Stock Fotografie ID: 2058520349

Effectiveness of the Sonicare For Kids Toothbrush in Preschool Children

A comparative study conducted as part of a graduation thesis in the field of Certified Dental Hygienist offers a comparison of the cleaning effectiveness of a manual toothbrush and a sonic toothbrush…
15. 10. 2023 Source: Dental Care
karcinom

Benefit of Adding Panitumumab to Maintenance Therapy in mCRC with Non-mutated RAS Oncogene

PANAMA was the first randomized study evaluating the addition of an anti-EGFR antibody to maintenance therapy with fluorouracil and folic acid (FU/FA) in patients with previously untreated metastatic…
14. 10. 2023 Source: Colorectal Cancer
chronická bolest_žena

Tapentadol Hydrochloride in Clinical Practice –⁠ To Whom, When, How, and Why?

Thanks to its specific properties, tapentadol hydrochloride ranks among the most effective opioids for managing chronic non-cancer pain. Unlike most opioids, it also exhibits an analgesic effect in…
12. 10. 2023 Source: Updates in Pain Treatment
Hakl

What a Decade of Experience with Tapentadol Hydrochloride in Pain Treatment Has Shown

In an interview with Dr. Marek Hakl, Ph.D., from the Brno Pain Treatment Center, we focus on the role of tapentadol hydrochloride in the treatment of chronic pain. We discuss, among other things, its…
12. 10. 2023 Source: Updates in Pain Treatment
plice

Long-term Benefit of Sotorasib for Survival of Patients with Pre-treated Advanced/Metastatic NSCLC with G12C Mutation of KRAS Oncogene

Sotorasib is indicated as monotherapy for advanced non-small-cell lung cancer (NSCLC) with the KRASG12C gene mutation, if there has been progression after ≥ 1 prior line of systemic therapy. The…
10. 10. 2023 Source: Lung Cancer
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