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INFOGRAPHIC: Post-Induction Therapy for AML –⁠ Current Guidelines

10. 10. 2023 Source: Acute Myeloid Leukemia

What are the recommended therapeutic modalities for consolidation and maintenance therapy of acute myeloid leukemia (AML) in patients over 60 years of age? We present a clear therapeutic algorithm according to the current recommendations of the American National Comprehensive Cancer Network.

Oral Azacitidine After Achieving Remission in AML Improves Survival and Does Not Worsen Quality of Life

Orally administered azacitidine as maintenance therapy in patients with acute myeloid leukemia (AML) after achieving remission provides a favorable effect in terms of fatigue and improving…

10. 10. 2023 Source: Acute Myeloid Leukemia

Improvement of Executive Functions in Therapy of Dravet Syndrome with Fenfluramine in Preschool Children

Dravet syndrome is a rare genetic progressive epileptic encephalopathy that is usually accompanied by intellectual and behavioral disorders. Many children with this syndrome also struggle with…

10. 10. 2023 Source: Rare Diseases in Neurology

Myasthenia Gravis and Unmet Patient Needs –⁠ Data from Clinical Practice

Myasthenia gravis (MG) is a rare, chronic, disabling, unpredictable, and potentially life-threatening autoimmune neuromuscular disease. There is still a lack of sufficient data from real clinical…

10. 10. 2023 Source: Rare Diseases in Neurology

Side Effects of Antipsychotics and Patient Preferences in the Treatment of Schizophrenia

Although a number of antipsychotics are currently available, many patients still suffer from unpleasant side effects associated with the treatment of schizophrenia. To determine how individuals with…

9. 10. 2023 Source: Modern Treatment of Schizophrenia

Physical Activity in Young Men with Hemophilia A

What may influence the inclusion of physical activity in the lifestyle of individuals with hemophilia? This was the focus of a Norwegian study published in the journal Haemophilia.

6. 10. 2023 Source: Hemophilia with Movement

N9-GP in Previously Treated Pediatric Patients with Hemophilia B –⁠ Extended Follow-up

An analysis of extended treatment with nonacog alfa pegol (N9-GP) in pediatric patients with hemophilia B evaluated the long-term safety and effectiveness of this prophylactic modality.

4. 10. 2023 Source: Hemophilia with Movement

artroplastika kyčelního a kolenního kloubu

Pain Management in Patients After Hip and Knee Arthroplasty –⁠ Data from Clinical Practice

Inadequate analgesia after hip and knee arthroplasty can result in delayed postoperative recovery accompanied by chronic pain. The retrospective study presented below compared the efficacy of…

3. 10. 2023 Source: Analgesia

Subcutaneous Immunoglobulin Therapy in Patients with Secondary Immunodeficiency –⁠ Real-World Data

Even in patients with secondary immunodeficiency (SID), immunoglobulin substitution can be indicated. Intravenous (IVIG) therapy is considered effective based on studies, but subcutaneous (SCIG) therapy...

2. 10. 2023 Source: Primary and Secondary Immunodeficiencies

Romiplostim in ITP Treatment –⁠ Data from German Clinical Practice

Real-world clinical practice data from Germany confirm the beneficial effect and safety profile of romiplostim in patients with immune thrombocytopenia (ITP), both newly diagnosed, persistent, and…

2. 10. 2023 Source: Immune Thrombocytopenia

Invasive Pneumococcal Disease –⁠ Current Czech Data

The number of reported cases of invasive pneumococcal disease (IPD) returned to levels comparable to those before the COVID-19 pandemic in 2022. Regarding age-specific morbidity, the most at-risk…

2. 10. 2023 Source: Regular Vaccination

Do Gliflozins Affect the Need to Use Diuretics?

Sodium-glucose cotransporter 2 inhibitors (SGLT2i, i.e., gliflozins) have advanced from their initial role in reducing hyperglycemia in the treatment of type 2 diabetes mellitus (DM2) to…

1. 10. 2023 Source: Heart Failure

Rapid Strengthening and Long-term Stabilization –⁠ New Strategy for Sequential Treatment of Severe Osteoporosis

Osteoanabolics have long been considered a treatment modality for osteoporosis that is only considered when antiresorptive medication lacks the desired efficacy. However, their role has been shifting…

27. 9. 2023 Source: Osteoporosis – Trends in Sequential Therapy

Inhibition of Sclerostin in Osteoporosis Therapy

Romosozumab, a subcutaneously administered antibody against sclerostin, is one of the most potent osteoanabolics and appears to be a highly effective modality in the treatment of postmenopausal…

27. 9. 2023 Source: Osteoporosis – Trends in Sequential Therapy

Doc. Tomáš Gabrhelík: Pain treatment should be seriously addressed by all fields, especially in seniors

Chronic pain is often underestimated, especially in older and polymorbid patients. On the other hand, during self-treatment, many patients use inappropriate medication for a long time. The treatment…

27. 9. 2023 Source: Analgesia

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