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News When and why to consider the diagnosis of myasthenia gravis in neurological practice, and what treatment options do we currently have?

Myasthenia gravis (MG) is a clinically heterogeneous disease characterized by fluctuating muscle weakness and fatigability that worsens after physical exertion or mental stress. Accurate diagnosis is essential because treatment can lead to permanent remission and full functional capacity of the patient.

Source: Rare Diseases in Neurology 2. 5. 2023

News Non-Invasive Diagnosis of Cardiac Amyloidosis

Cardiac amyloidosis has always been considered a rare pathology. However, thanks to advancements in imaging methods and laboratory tests, it is now evident that it might be responsible for a larger amount of cardiac diseases than previously thought. Which non-invasive diagnostic methods are useful in identifying cardiac amyloidosis?

Source: Amyloidosis 16. 1. 2023

News News in Laboratory Diagnostics of Early Sepsis −⁠ First Czech Experiences

Sepsis represents one of the most frequent causes of morbidity and mortality in critically ill patients. Laboratory markers play an important role in the diagnosis and prognosis of septic states. The aim of the study by the Czech authors was to evaluate the diagnostic yield of new laboratory markers in the form of monocyte distribution width and specific markers on the surface of neutrophil granulocytes.

Source: Because 29. 11. 2021

News How to recognize amyloidosis as a cause of heart failure?

Although the fate of patients with heart failure has improved in recent decades, it remains a disease with a poor prognosis that significantly worsens the quality of life. The prevalence of heart failure is 1-2% in the adult population, but it increases with age and is more than 10% in people over 70. In addition to well-known causes, some rare nosological units, such as amyloidosis, can also be behind the development of heart failure.

Source: Amyloidosis 24. 2. 2022

News Updated Recommendations for Treatment of von Willebrand Disease

In 2021, new recommendations for the therapy of von Willebrand disease (vWD) were published, based on a consensus by the American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), the National Hemophilia Foundation (NHF), and the World Federation of Hemophilia (WFH). The recommendations comprise a total of 12 points and address not only prophylaxis but also gynecological and obstetric issues, for example.

Source: Von Willebrand Disease 28. 4. 2022

Články časopisu Cholangiocarcinoma: a pathologist’s point of view

Author of the article: J. Hrudka, E. Sticová Source: Rozhledy v chirurgii | 10/2022 8. 11. 2022

News Dust Mite Allergies: Common Does Not Mean Trivial

Dust mite allergies are almost ubiquitous problems that we perceive as part of the 'broader norm.' However, patients do not see it this way, so we should not lose sight of it.

Source: Dust Mite Allergy 22. 7. 2021

Články časopisu Ovarian epithelial malignant tumors in adolescence

Author of the article: Luboš Minář, Z. Ivanová, E. Jandáková Source: Česká gynekologie | 2/2014 21. 4. 2014

Články časopisu A new definition of status epilepticus and its pharmacological management

Author of the article: O. Strýček, V. Šrámek Source: Anesteziologie a intenzivní medicína | 4/2018 24. 9. 2018

News Long-Term Effect of Nuclear Magnetic Resonance Therapy on Osteoarthritis –⁠ An Unconventional Case Report

Osteoarthritis is among the most common health issues in adults, with its prevalence increasing with advancing age. There is currently no causal therapy for the disease; hence, the standard approach is symptomatic treatment with surgical joint reconstruction in advanced stages of the disease. The presented case report describes a successful case of long-term therapy for osteoarthritis using molecular biophysical stimulation.

Source: Treatment of the Musculoskeletal System 21. 2. 2020

Články časopisu Breast cancer in elderly patients over 70 years of age

Author of the article: J. Gatěk, V. Petrů, P. Kosáč, J. Šťastný, M. Ratajský, J. Duben, B. Dudešek, M. Zábojníková, D. Vrána Source: Rozhledy v chirurgii | 1/2018 7. 1. 2018

News Overuse of Corticosteroids as a Serious Problem in ITP

Corticosteroids (CS) are a common part of the treatment for immune thrombocytopenia (ITP). However, their administration is associated with significant short-term and long-term toxicity, and the goal should be to minimize their use to the shortest possible duration. Early combination with other medications could be helpful in this regard.

Source: Immune Thrombocytopenia 9. 5. 2023

Články časopisu Deep vein thrombosis and pulmonary embolism in pregnancy

Author of the article: J. Mannová, M. Penka, P. Štourač Source: Anesteziologie a intenzivní medicína | 2/2017 18. 5. 2017

News Chronic Thromboembolic Pulmonary Hypertension –⁠ Overview of Pathophysiology, Diagnosis, and Treatment

Chronic thromboembolic pulmonary hypertension (CTEPH) is defined by the 2015 ESC/ERS guidelines as symptomatic pulmonary hypertension with persistent defects in lung perfusion despite adequate anticoagulation therapy. Significant values for determining a diagnosis of pulmonary hypertension are a mean pulmonary artery pressure > 25 mmHg. However, this condition remains significantly underdiagnosed, mainly due to its nonspecific symptoms.

Source: Pulmonary hypertension (CTEPH, PAH) 9. 6. 2020

News Extract of Medical Cannabis Now Available for Czech Patients. What Benefits Does It Bring?

At the end of 2022, a new drug based on cannabis extract Naxiva Panaxol by Neuraxpharm was approved in the Czech Republic. It can be prescribed by specialists treating patients with chronic intractable pain. The treatment is covered by public health insurance.

Source: Medical Cannabis 17. 3. 2023