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News Off-label use of eye drops containing bromfenac in the treatment of cystoid macular edema in the only seeing eye of a complex patient –⁠ case report

The following case report discusses the effect of repeated use of an ophthalmic preparation containing bromfenac in a patient with recurrent cystoid macular edema (CME) in the only seeing eye with advanced glaucoma. The patient has undergone more than 15 eye surgeries or procedures, has been treated for glaucoma since 2005, and has multiple intolerances to eye drops and polymorphic problems, which she attributes to the application of the drops. The dominant personality trait is an anxious approach, which, together with the complicated findings in the only seeing eye, narrows the selection of therapeutic options.

Source: Treatment of Glaucoma 14. 6. 2024

News The Latest Updates of ESC Recommendations for Heart Failure Treatment

What is new in heart failure therapy? At the annual congress of the European Society of Cardiology (ESC), held from August 25–28, 2023 in Amsterdam, updates to clinical guidelines were traditionally presented. One of these was an update to the 2021 recommendations concerning the diagnosis and treatment of acute and chronic heart failure (HF). Below you will find a brief summary of the key changes.

Source: Heart Failure 18. 10. 2023

Články časopisu Fracture Liaison Service: pilot project in FH Královské Vinohrady

Author of the article: Kučerová Tereza, Suchoťko Vasyl, Malá Julia, Sotorník Richard, Švec Jan, Kirchhofová Kateřina, Skála-Rosenbaum Jiří, Brunerová Ludmila Source: Clinical Osteology | 1-2/2023 26. 4. 2023

Články časopisu Evolution of chronic lymphocytic leukemia treatment over the past 25 years

Author of the article: T. Papajík, R. Urbanová, P. Turcsányi Source: Transfuze a hematologie dnes | 1/2019 29. 3. 2019

News How Important is the Time Factor in the Treatment of Heart Failure?

Current guidelines emphasize the importance of early diagnosis and immediate treatment for patients with heart failure (HF). These patients are most vulnerable immediately after the decompensation of chronic HF, and intensive treatment can therefore reduce the risk of further hospitalization and mortality. The prognosis for these patients is unfavorable, and any delay in initiating therapy further worsens it. The treatment of chronic HF is often postponed if the symptoms are stable, and the risk of adverse outcomes and sudden death is underestimated. The time factor thus plays a significant role in all stages of HF.

Source: Heart Failure 13. 11. 2023

News MUDr. Petra Garnolová: The combination of medical cannabis with other analgesics is the ideal way to achieve the best effect with the fewest side effects

Medical cannabis is gradually finding its way to many patients with various ailments, including those with unmanageable and hard-to-influence chronic pain. For them, this therapy can offer a new chance at a quality life despite severe or terminal illness. A relatively new form that brings additional benefits is the extract of medical cannabis. We spoke with MUDr. Petra Garnolová, a specialist in clinical oncology and palliative medicine, about why it is worth considering not only as part of analgesic therapy and her experiences from real practice.

Source: Medical Cannabis 8. 1. 2024

News CASE STUDY: Oral Semaglutide in a Young Diabetic = Weight Loss and CV Risk Reduction, Better Adherence and Treatment Comfort

Diabetologist MUDr. Tomáš Pfohl from the Regional Hospital Liberec illustrates the benefits of therapy with oral semaglutide in a relatively young diabetic patient with type 2 DM after unsatisfactory disease compensation was not achieved with a combination of gliptin and metformin.

Source: Modern Treatment of Diabetes with GLP-1 Analogues 10. 6. 2024

Články časopisu Chronic lymphocytic leukaemia –⁠ contemporary application of modern prognostic and predictive markers in diagnostics

Author of the article: Š. Pospíšilová, M. Jarošová, M. Doubek Source: Transfuze a hematologie dnes | 1/2019 29. 3. 2019

Články časopisu Comorbidities of Alzheimer‘s disease –⁠ results of a multicentric observational COSMOS study in the Slovak Republic

Author of the article: M. Minár, J. Dragašek, I. Mátéffy, P. Valkovič Source: Česká a slovenská neurologie a neurochirurgie | 1/2020 5. 2. 2020

News Patient with Diabetes: When to Follow Up and When to Refer to a Specialist?

It is most often the general practitioner (GP) who first diagnoses diabetes. Whether during preventive check-ups, preoperative examinations, or based on the patient's clinical issues. After diagnosing diabetes, however, the GP faces a difficult decision: Will they continue to monitor and treat the patient themselves, or will they refer them to a diabetologist?

Source: Diabetes 6. 12. 2020

Články časopisu Transcranial sonography of the medial temporal lobe in Alzheimer’s disease patients

Author of the article: D. Školoudík, P. Krulová, H. Kisvetrová, R. Herzig, J. Blahuta, T. Soukup Source: Česká a slovenská neurologie a neurochirurgie | 2/2020 8. 4. 2020

News How do patients perceive the change in appearance of chronically used medications and to what extent does it lead to non-adherence to therapy?

Doctors regularly encounter patients in their offices who complain about changes in the appearance of their chronically used medications. Such a change can even be the cause of non-adherence to treatment. Interesting findings on this topic were brought by an American survey aimed at identifying the preferences, experiences, and reactions of patients and pharmacists related to changes in the appearance of medications.

Source: Cardiovascular Continuum 23. 2. 2022

Články časopisu Diabetes and Schizophrenia

Author of the article: L. Ustohal1ihash2 Source: Česká a slovenská neurologie a neurochirurgie | 1/2012 20. 1. 2012

News If Suicides Were COVID-19... or Why We Still Overlook a Significant Cause of Premature Deaths?

More than a year since the start of the pandemic, the SARS-CoV-2 coronavirus has claimed 2.8 million lives globally, with 127 million recorded cases of COVID-19 (as of March 29, 2021). According to World Health Organization (WHO) data, there are 800,000 suicides annually, with suicide attempts being up to 20 times more frequent, totaling over 16 million. Given our current focus on physical health, are we overlooking the extent and importance of mental health issues in the population? This question has been raised by several experts from different countries in their submission to the February issue of The Journal of Clinical Psychiatry.

Source: Depression and Anxiety 30. 3. 2021

News Fatigue and Quality of Life in Patients with Primary Biliary Cholangitis

Fatigue is the most common symptom of primary biliary cholangitis (PBC). Its occurrence significantly impacts the health-related quality of life of patients.

Source: Primary Biliary Cholangitis 8. 3. 2021