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News Glucagon for Intranasal Application Newly Available Also in the Czech Republic
Intramuscular administration of glucagon was until recently the only option for acute treatment of hypoglycemia with impaired consciousness at home. However, since July this year, the Baqsimi product – glucagon for intranasal application – is newly available in the Czech Republic.
News Anabolic Antiosteoporotic Treatment as a First Step in Patients with Very High Fracture Risk
According to the 2022 opinion of the ESCEO (European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases) working group, it is advisable to identify patients with osteoporosis who have a very high risk of fracture and to use an anabolic antiosteoporotic drug as the initial pharmacotherapeutic intervention, followed by necessary antiresorptive treatment to be addressed over the entire expected length of life.
News Use of Bilastine in Pediatrics − Pathway to Improving Concentration and Performance of Young Allergy Sufferers
In the treatment of allergic diseases, especially in children, safety, good tolerability, simple dosing regimen, and non-sedative effects are the basic requirements for administered medications. Sedative side effects of treatment have a negative impact on sleep patterns and subsequently on children's performance in school. European professional societies recommend the use of modern second-generation antihistamines in the treatment of children. Studies confirm that bilastine, which meets these requirements, should be among the first-choice drugs.
News Sequential Treatment of Schizophrenia – Interactive Case Study
Sequential treatment of schizophrenia helps psychiatrists clarify the stage of the patient's treatment and how to further guide pharmacotherapy. The following case study illustrates the possibilities for reducing negative and cognitive symptoms of schizophrenia while adhering to a metabolically sparing treatment approach.
News How Gut Microbiota Affects Thyroid Function
The composition of gut microbiota has a significant impact on the human body. Studies conducted so far have found a correlation between dysbiosis and a range of diseases, including thyroid disorders (primarily autoimmune, but also the occurrence of nodules or thyroid cancer).
News Current Indications for Negative Pressure Therapy in Wound Healing in Orthopedic and Traumatological Patients
Negative pressure wound therapy was introduced in North America in 1997. Since then, the method has gained great popularity and is used in the treatment of many acute and chronic wounds. Like any other treatment modality, it has its proper indications and contraindications. An overview article by French authors evaluates the current use of negative pressure therapy in the fields of orthopedics and trauma of the musculoskeletal system.
News What Benefits Does the Fixed Combination of Candesartan/Amlodipine Bring?
A relatively new fixed combination used in the treatment of hypertension is represented by candesartan/amlodipine, that is, a sartan and a calcium channel blocker. Its advantage compared to the combination of ACE inhibitor/calcium channel blocker is primarily the lower occurrence of side effects.
News Correct Selection of Appropriate Incontinence Aid is Crucial for Addressing Patient's Difficulties
Urinary incontinence is an uncomfortable issue that can be resolved by choosing the right incontinence aids. Selecting a quality product is most important for the patient − it affects their comfort and mental well-being, but choosing the right aid can also be complicated for doctors. The market offers many products of different brands and qualities, where the absorption capacity is often the main selection criteria. However, other important aspects must also be considered.
News Effect of 3 Different Doses of Trazodone on QT Interval Length
Patients diagnosed with depression often also suffer from cardiovascular diseases, including heart failure. Given the increased risk of death in such comorbid patients, the safety and efficacy of the antidepressant must be considered when choosing one.
News Wound Healing and Exudate – A Comprehensive Look at Moisture Management in Wounds
Exudate produced during the inflammatory phase of healing is a crucial factor that ensures a moist environment in the wound, provides nutrients for cellular metabolism, and supports autolytic debridement. Without proper exudate management and maintenance of optimal moisture in the wound, patients are exposed to a range of risks and complications in healing.
News Options for Systemic Therapy of Advanced Stage Small Cell Lung Cancer
Small cell lung cancer (SCLC) is the most aggressive type of lung tumor. Although it responds well to chemotherapy and radiotherapy, due to the early onset of treatment resistance, the 5-year survival rate is less than 10%. After more than 30 years of very limited progress in treating advanced SCLC patients, immune checkpoint inhibitors (checkpoints) have been introduced to the market, significantly prolonging survival. What are the current recommendations for treating patients with advanced SCLC?
News Kadcyla in a New Indication – Adjuvant Therapy for Early HER2+ Breast Cancer
In December, the European Commission approved the expansion of the indication for Roche's medicinal product Kadcyla, which contains the active substance trastuzumab emtansine. This expansion makes adjuvant treatment accessible to a much larger number of patients with early HER2-positive breast cancer and reduces the likelihood of disease recurrence or progression.
News According to which parameters can we best assess the quality of incontinence aids?
Properly chosen incontinence aid significantly influences the user's quality of life. When selecting incontinence aids, it is very important to consider their individual properties and parameters. While in European countries the absorbency of the aid is mainly assessed alongside the product's size and the user's gender, other parameters are evaluated elsewhere in the world. So what should we primarily focus on when choosing an aid?
News New Solution for Moderate Incontinence – Discreet Pull-Up Diaper Pants
The range of products for people with incontinence is constantly expanding – recent additions include pull-up diaper pants labeled Seni Active Basic and Seni Active Classic.